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Dipyridamole Coupon - Dipyridamole 75mg tablet

dipyridamole

Generic Persantine
Used for Heart Attack
Used for Heart Attack

Dipyridamole is an antiplatelet medication that keeps blood clots from forming. It's often used with another blood thinner called warfarin (Coumadin). It helps lower the risk of clots in people who've had heart valve replacement surgery. You take dipyridamole 4 times a day, with or without food. The most common side effects are dizziness and upset stomach. Its brand name Persantine is no longer sold, but the generic version of dipyridamole is still available.

Reviewed by:
reviewer
Robert Chad Hakim, PharmD, BCCCP
reviewer
Cydnee Ng, PharmD
Last reviewed on May 9, 2025
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageInteractionsCostAlternativesLatest newsImagesPricesMedicare
basics-icon

What is Dipyridamole?

What is Dipyridamole used for?

How Dipyridamole works

Dipyridamole is an antiplatelet medication. It works by blocking your platelets from clumping up together. This helps prevent blood clots from forming.

Are you looking for information on Aggrenox (aspirin / dipyridamole extended-release) instead?
When does Dipyridamole start working?
Time passed since treatment started:
MINUTES
HOURS
DAYS
WEEKS
MONTHS
Full effect

Drug Facts

Common BrandsPersantine (brand name no longer available)
Drug ClassAntiplatelet
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
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Avg retail price
$196.77(save 79.75%)
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$39.84
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What are the side effects of Dipyridamole?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Dizziness (14%)
  • Stomach discomfort (6%)
  • Headache (2%)
  • Rash (2%)

Other Side Effects

  • Diarrhea
  • Nausea
  • Vomiting
  • Indigestion
  • Flushing
  • Itching
  • Fatigue
  • Muscle or joint pain
  • Low blood pressure
Note: Side effects were reported by people taking dipyridamole with warfarin (Coumadin).

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Liver problems: swelling of your stomach, yellowing of your skin or the whites of your eyes, confusion

Source: DailyMed

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Rare

Chest pain

gallstones

tightness or swelling of neck

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Abdominal or stomach cramps

diarrhea

dizziness or lightheadedness

Less common

Flushing

headache

nausea or vomiting

weakness

Rare

General discomfort and/or unusual tiredness or weakness

hair loss

joint pain or swelling

muscle pain

runny nose

sneezing

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Dipyridamole

thumbs-up

Pros

Taken by mouth

Can take with or without food

thumbs-down

Cons

Not a preferred option

Need to take it four times a day

Can lower blood pressure

pharmacist-tips

Pharmacist tips for Dipyridamole

pharmacist

  • Take dipyridamole 4 times a day, about 6 hours apart, with or without food. It's a good idea to take it at about the same times each day. This helps you remember to take your medication.

    • Swallow dipyridamole tablets whole. Don't crush, chew, or cut the tablets because this can change how much medication gets absorbed into your body. Talk to your prescriber if you have trouble swallowing it whole.

      • You might feel dizzy after taking dipyridamole because it can lower your blood pressure. If you feel dizzy or lightheaded, sit or lie down until you feel better. Tell your prescriber if this happens. Don't drive until you know how dipyridamole affects you.

        • Side effects like dizziness and stomach discomfort can happen when you start taking dipyridamole. These usually get better or go away over time. But talk to your prescriber if any side effects bother you too much or don't go away. Your prescriber can help you manage side effects.

          • It's a good idea to avoid alcohol while taking dipyridamole. Alcohol can make side effects like dizziness and stomach upset worse.

            • Tell your prescriber if you're pregnant, thinking of getting pregnant, or are breastfeeding. It's not known how safe dipyridamole is during pregnancy or while breastfeeding. Your prescriber can help you understand the risks and benefits to decide what's best for you and your baby.

              faqs

              Frequently asked questions about Dipyridamole

              Is dipyridamole safe?
              Dipyridamole is usually safe when you take it the way your prescriber instructs you to. Like any other medication, it can have side effects. With dipyridamole, you might feel dizzy or have an upset stomach. These side effects often get better over time. If they bother you or don't go away, talk to your prescriber.
              Is dipyridamole a blood thinner?
              Yes, dipyridamole is a type of blood thinner called an antiplatelet medication. It stops the platelets in your blood from clumping up together. This helps stop blood clots from forming.
              Is dipyridamole an anticoagulant?
              No, dipyridamole isn't an anticoagulant. It's an antiplatelet. Both classes of medications can help prevent blood clots from forming, so they're often called "blood thinners." But they work in different ways and are sometimes used in different situations. Dipyridamole is usually taken along with warfarin (Coumadin), which is an anticoagulant.
              Who should not take dipyridamole?
              Children 12 years and younger shouldn't take dipyridamole. This medication hasn't been studied in this age group, so we don't know if it works well or is safe for them. Also, some people with certain health conditions need to be more careful with dipyridamole because it might cause more problems. This includes people with heart problems, low blood pressure, or liver issues. It also includes those taking certain medications for dementia or Alzheimer's disease. Tell your prescriber about all your medical conditions and medications you take. This helps them make sure dipyridamole is safe for you.
              What's the difference between dipyridamole and aspirin?
              Dipyridamole and aspirin are both antiplatelet medications. They both work to help stop blood clots from forming. They can lower the risk of clots after heart valve replacement surgery. But dipyridamole is taken 4 times a day, while low-dose aspirin is only taken once a day. Cardiologists usually prefer low-dose aspirin over dipyridamole because there's stronger evidence that it helps prevents serious problems, like strokes. Talk to your prescriber about your options.
              What foods should you avoid when taking dipyridamole?
              There are no specific foods that cause problems with dipyridamole. But remember, you usually take this medication with warfarin (Coumadin), another blood thinner. Warfarin (Coumadin) has important food interactions that you should know about. These include foods high in vitamin K (like dark, leafy greens), avocado, and mango. Speak with your care team to learn more.
              How long does it take for dipyridamole to work?
              Dipyridamole starts working in about 20 minutes to help prevent clots from forming. If you have questions about how fast the medication works, ask your prescriber.
              Is dipyridamole still available?
              Yes, dipyridamole is still available. Ask your prescriber or pharmacist if you have other questions about availability.
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              What are the risks and warnings for Dipyridamole?

              Dipyridamole can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

              risk-warning

              Low blood pressure

              • Risk factors: Not enough fluid in your body (dehydration) | Having diarrhea or vomiting for a long time | Taking other medications that can lower your blood pressure | History of low blood pressure | Severe heart disease

                Dipyridamole can make your blood pressure go down. This can make you feel dizzy, tired, or lightheaded. Tell your prescriber if you have heart problems or usually have low blood pressure. They can check that dipyridamole is safe for you.

                it's important to drink plenty of fluids while taking dipyridamole. Be sure to stay hydrated when you have a lot of diarrhea, vomit a lot, or sweat too much. If you get dehydrated (don't have enough fluids in your body), your blood pressure could drop even more.

                If you feel dizzy, lightheaded, faint, or tired, sit down slowly while holding onto something so you don't fall. Let your prescriber know if this happens while you're taking dipyridamole. If you ever feel confused or fall and hit your head, get medical help right away.

                risk-warning

                Liver damage

                Some people who took dipyridamole had higher liver enzyme levels on their blood tests. This can be a sign of liver damage. In some cases, liver problems can be serious and might even lead to liver failure.

                Tell your prescriber if you've had liver problems before. You might need to get blood tests done before starting dipyridamole and during treatment. This helps your prescriber check your liver health.

                Get medical help right away if you notice yellow skin or eyes, a swollen belly, stomach pain, or confusion. Also get help if you have black, tarry, or bloody stools or dark or brown urine. These could be signs of liver damage. Your prescriber can check to see if you need to stop taking dipyridamole to keep your liver safe.

                dosage

                Dipyridamole dosage forms

                The average cost for 90 tablets of 75mg of Dipyridamole is $39.84 with a free GoodRx coupon. This is 79.75% off the average retail price of $196.77.
                tablet
                Tablet
                DosageQuantityPrice as low asPrice per unit
                25mg180 tablets$43.39$0.24
                50mg180 tablets$47.48$0.26
                75mg90 tablets$39.84$0.44

                Typical dosing for Dipyridamole

                The typical dose ranges from 75 mg to 100 mg by mouth four times a day. It's usually taken with warfarin (Coumadin).

                Dipyridamole is also available as an intravenous injection (IV) that's administered by a healthcare professional at a medical center.

                interactions

                Interactions between Dipyridamole and other drugs

                Dipyridamole may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Dipyridamole. Please note that only the generic name of each medication is listed below.

                Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

                • Defibrotide
                • Riociguat

                Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

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                How much does Dipyridamole cost?

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                Dipyridamole (generic)
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                alternatives

                What are alternatives to Dipyridamole?

                There are a number of medications that your doctor can prescribe in place of Dipyridamole. Compare a few possible alternatives below.
                Dipyridamole
                Used for:
                $39.84 Lowest GoodRx priceView Prices
                Aspirin
                Used for:

                • Pain relief from minor aches and pains, such as from headaches, muscle pain, toothache, menstrual cramps, and arthritis

                • Fever

                • Heart protection (lower the risk for heart attack or stroke) in certain adults - low-dose aspirin (81 mg per day) only

                $2.80 Lowest GoodRx priceView Prices
                Warfarin (Coumadin)
                Used for:

                • Prevention and treatment blood clots in the veins

                • Prevention and treatment blood clots linked to atrial fibrillation (AFib) or heart valve replacement

                • Prevention of more blood clots and to lower risk of death after a heart attack

                $4.00 Lowest GoodRx priceView Prices
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                Dipyridamole images

                White Round Ani And 237 - Dipyridamole 75mg Tablet
                This medicine is White, Round Tablet Imprinted With "Ani" And "237".White Round Ani And 237 - Dipyridamole 75mg Tablet
                Yellow Round 183 And O - Dipyridamole 75mg Tablet
                This medicine is Yellow, Round Tablet Imprinted With "183" And "O".Yellow Round 183 And O - Dipyridamole 75mg Tablet

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