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COVID-19 and Shingles: What’s the Connection? Experts Discuss (With Pictures)

Shiv Sudhakar, MDPatricia Pinto-Garcia, MD, MPH
Written by Shiv Sudhakar, MD | Reviewed by Patricia Pinto-Garcia, MD, MPH
Reviewed on December 2, 2025

Key takeaways:

  • Shingles is a painful skin condition caused by the reactivation of the chickenpox virus.

  • Research suggests that people are at higher risk of developing shingles during a COVID-19 illness.

  • The shingles vaccine can keep you safe from developing shingles. You can get the shingles and COVID vaccines at the same time.

Shingles is a painful skin condition that people can develop as they get older or if they have a weakened immune system. 

Any type of infection can stress the immune system and cause a shingles outbreak. The virus that causes COVID-19 is no exception. Research continues to show a relationship between COVID and shingles. But how exactly are shingles and COVID related?  

What is shingles?

Shingles is a painful rash that develops when the varicella-zoster virus (the virus that causes chickenpox) gets reactivated. Before the chickenpox vaccine, many people got chickenpox in childhood. Even after people completely recover from chickenpox, the varicella virus can stay “asleep” (dormant) in the body by hiding in the nervous system without causing any symptoms. But when the immune system gets weakened, the virus can “wake up” (reactivate) and cause shingles. 

Only people who’ve had chickenpox in the past can get shingles. In theory, people who’ve been vaccinated against chickenpox can develop shingles. But this doesn’t happen very often

It’s important to recognize shingles when it develops. Shingles can lead to complications like long-term nerve pain and keratitis, a vision-threatening eye infection.

Shingles pictures

Here are some shingles rash images on different skin tones and various parts of the body. 

Close-up of shingles on the face.
A shingles rash appears on the face.
Early-stage shingles on the chest.
Early shingles forms on the chest.
Shingles outbreak on the back.
A shingles rash appears on the back.

Can COVID-19 illness cause shingles?

The virus that causes COVID doesn’t cause shingles directly. But COVID and shingles may be related. COVID illness weakens the immune system, and that can give the virus a chance to wake up and cause shingles. Here’s what the research shows so far:

  • A review of studies found that people with COVID illness were twice as likely to develop shingles compared to people who did not get sick with COVID.

  • Another study found that people were more likely to develop shingles if they'd been sick with COVID within the last year. This study also found that people were more likely to develop complications from shingles if they'd recently had a COVID illness.

  • Another very large study found that people older than 50 years were 15% more likely to develop shingles if they had COVID illness when compared with people of the same age who didn’t get COVID. 

Scientists can’t say for sure that having COVID increases everyone’s risk of developing shingles. But people who are older or have medical conditions that affect the immune system should be aware of this risk. 

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Does the COVID-19 vaccine cause shingles?

No. The COVID vaccine doesn’t cause shingles — only the varicella-zoster virus causes shingles. But it’s not clear if COVID vaccines can trigger shingles to develop.

There have been reports of people developing shingles after COVID vaccination. But it’s unclear if these cases are just coincidence or if shingles is a real possible side effect of the COVID vaccine. 

One study reviewed reports of people who developed shingles after the COVID vaccine. The study found that many of these people had medical conditions that weakened their immune systems. 

In a study from Israel, everyone who got shingles after the COVID vaccine was also taking immunosuppressive medications. 

If you have a weakened immune system or are taking immunosuppressive medication, you may be at increased risk for developing shingles after your COVID vaccine. But keep in mind that you may also be at risk for developing shingles from COVID illness.  

Does the COVID-19 vaccine protect against shingles?

No. The COVID vaccine doesn’t protect against shingles. The virus that causes shingles is different from the virus that causes COVID. So the same vaccine can’t protect against both viruses. 

But there’s an effective vaccine against shingles. The CDC recommends the shingles vaccine (Shingrix) for everyone older than 50 years. The CDC also recommends it for anyone older than 19 years who has a weakened immune system.

If you’re at higher risk for developing shingles from COVID or the COVID vaccine, it’s a good idea to keep your shingles vaccination up to date. You can get your shingles and COVID vaccines at the same time. 

How soon can you get the shingles vaccine after COVID infection?

If you currently have COVID illness, you may be able get your shingles vaccine as soon as your illness improves and your isolation period ends. And if you have shingles, you may be able to get your COVID vaccine once you’re feeling better. 

It’s best to talk about the timing of your vaccines with a healthcare professional. You may need to wait a bit longer before getting vaccinated if you have certain medical conditions or take certain medications. 

Frequently asked questions

Yes. It’s possible to get shingles after getting the shingles vaccine. But, it’s very uncommon. Studies show that the Shingrix vaccine is 97% effective in preventing shingles in adults 50 to 69 years old and 91% effective in those 70 years and older. 

There are a few different shingles triggers that can cause it to activate. Common ones include: 

  • Getting older

  • Having a weakened immune system

  • Having an organ transplant 

  • Physical or emotional stress

  • Being female 

Yes, but it’s unlikely. In fact, one study showed that it happened in about 6% of people. When shingles does happen twice, the interval between episodes is usually years. However in some people, it can be as little as a few months.

The bottom line

Shingles is a painful skin rash that’s caused by the reactivation of the chickenpox virus. Shingles can be triggered by stress, illness, and a weakened immune system. There are reports of people getting shingles with COVID illness and after the COVID vaccine. Research shows that people who are older than 50 years or have a weakened immune system are more likely to develop shingles with COVID illness. Getting vaccinated against shingles can keep you safe from developing the illness. 

Images used with permission from VisualDx (www.visualdx.com).

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Why trust our experts?

Shiv Sudhakar, MD, is a fellow of the Infectious Disease Society of America and works as a physician in California. He has co-authored over 10 peer-reviewed research articles and given 20 scientific presentations.
Patricia Pinto-Garcia, MD, MPH, is a medical editor at GoodRx. She is a licensed, board-certified pediatrician with more than a decade of experience in academic medicine.

References

GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.

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