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Compare Pred Forte vs. Durezol

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Prednisolone acetate (Pred Forte) and Durezol (difluprednate) are both corticosteroid eye drops used to treat inflammation, but they have some differences. Prednisolone acetate is used for eye injuries, swelling, and allergies, and used 2 to 4 times daily depending on the condition. In contrast, Durezol is used mainly for eye inflammation and pain after surgery, and is typically used 4 times a day for at least 2 weeks. Prednisolone acetate and Durezol can both cause eye irritation, but Durezol specifically slows down healing and can lead to higher eye pressure and cataracts with long-term use. Both medications are available as lower-cost generics.

  • Prednisolone eye drops
    Difluprednate (Durezol)
  • Prednisolone eye drops
    Difluprednate (Durezol)

  • Summary of Pred Forte vs. Durezol

    Summary for Corticosteroid
    Prescription only

    Prednisolone eye drops is a type of steroid eye drop. It helps treat eye inflammation in adults and children. The medication helps relieve symptoms like itchy eye, eye redness, and swelling in the eye. Prednisolone eye drops come as a generic as well as brand names like Pred Forte and Pred Mild. This eye drop is usually used in the affected eye(s) 2 to 4 times a day. Side effects can include temporary burning and stinging in the eye when you put the drops in.

    Summary for Corticosteroid
    Prescription only

    Difluprednate 0.05% eye drops, also known by its brand name Durezol, is a prescription corticosteroid that's used to treat eye inflammation. It's approved for adults and children who've just had eye surgery or who have anterior uveitis. The drops are placed directly in the eye(s) 4 times per day for at least 2 weeks. After this time, your prescriber will slowly lower your dose until it's safe to stop the medication altogether. Typical side effects include swelling in the front of the eye and light sensitivity. Difluprednate (Durezol) is available as a generic.

  • Indications of Pred Forte vs. Durezol

    Indications for
    •Eye inflammation
    Indications for
    •Eye inflammation and pain from eye surgery
    •Endogenous anterior uveitis

  • Pros and Cons of Pred Forte vs. Durezol

    Pros and Const for Corticosteroid
    Pros
    •Few side effects
    •Approved for both adults and children
    Cons
    •Might have to use the eye drops up to 4 times a day
    •Some formulations contain sulfite, so not a good option for people with a sulfite allergy
    Pros and Const for Corticosteroid
    Pros
    •Works well to lessen eye inflammation and eye pain
    •Few side effects since the medication is placed directly into the eyes
    •Approved for people of all ages
    Cons
    •Need to use four times a day
    •Can't use if you have an eye infection
    •Might be difficult for some people to use correctly

  • Common Side Effects of Pred Forte vs. Durezol

    Common Side Effects for
    •Temporary burning or stinging in the eye
    •Feeling like there's something in your eye
    Common Side Effects for
    •Eye swelling (up to 15%)
    •Eye redness (up to 15%)
    •Eye pain (up to 15%)
    •Eye sensitivity to light (up to 15%)

  • Warnings of Pred Forte vs. Durezol

    Common Side Effects for
    •Risk of eye infection when used for a long time
    •Risk of eye problems when used for a long time
    •Slow healing of the eye after cataract surgery
    •Severe allergic reaction
    Common Side Effects for
    •For use in the eye only
    •Possible eye infections and eye problems when used for a long time
    •Slow healing of the eye after an eye procedure
    •Damage to contact lenses

  • Prices with our coupons for Pred Forte vs. Durezol

    Learn more about Prednisolone eye drops
    Learn more about Difluprednate

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