Compare Clobazam vs. Clonazepam
Head-to-head comparisons of medication uses, side effects, warnings, and more.
- Clobazam (Onfi)Clonazepam (Klonopin)
- Clobazam (Onfi)Clonazepam (Klonopin)
Summary of Clobazam vs. Clonazepam
Summary for BenzodiazepinePrescription onlyClobazam (Onfi) is used to treat seizures in people ages 2 years and older with Lennox-Gastaut syndrome (LGS). The medication belongs to the drug class known as benzodiazepines, which work by slowing down activity in the brain. Clobazam (Onfi) is available as a lower-cost generic tablet and oral liquid suspension, and it's taken by mouth twice per day. Possible side effects include sleepiness, fever, and vomiting.
Summary for BenzodiazepinePrescription onlyClonazepam (Klonopin) is a benzodiazepine. It's approved to treat seizures in adults and children, and panic disorder in adults only. Clonazepam (Klonopin) is taken by mouth, typically two or three times a day. It's also available as orally disintegrating tablets (ODTs) for people who have trouble swallowing. Some common side effects of this medication include drowsiness, dizziness, and poor movement control. Before stopping clonazepam (Klonopin), speak with your prescriber to come up with a plan to lower your dose slowly over time to avoid withdrawal symptoms.
Indications of Clobazam vs. Clonazepam
Indications for•Treatment of seizures from Lennox-Gastaut syndrome in people ages 2 years and older (as an add-on to other anti-seizure medications)Indications forPros and Cons of Clobazam vs. Clonazepam
Pros and Const for BenzodiazepinePros•Works well to control the number of seizures you have if you have Lennox–Gastaut syndrome•Can give to children 2 years of age and older•Comes as a liquid, which is helpful if you have trouble swallowing pills•Doesn't have many drug interactions compared to other anti-seizure medicationsCons•Only approved for seizures related to Lennox-Gastaut syndrome•Need to take with other anti-seizure medications•Might lead to tolerance (doesn't work as well after you've taken it for a while)•Might have more frequent seizures if you suddenly stop taking the medicationPros and Const for BenzodiazepinePros•Taken by mouth•Less likely to cause rebound anxiety (in people with panic disorders) when stopping compared to some other benzodiazepines•Available as a lower-cost generic•Available as orally disintegrating tablet (ODT)Cons•Taken 2 to 3 times daily•Can be habit-forming, so isn't typically used for long-term treatment•Can cause memory problems, drowsiness, dizziness, and confusion•Might not work as well for seizure control over timeCommon Side Effects of Clobazam vs. Clonazepam
Common Side Effects for•Sleepiness (26%)•Fever (13%)•Low energy (10%)•Drooling (9%)•Acting aggressive or being angry or violent (8%)•Vomiting (7%)Common Side Effects forSeizures:
•Drowsiness (50%)•Poor movement control, clumsiness (30%)•Behavior problems (25%)Panic Disorder:
•Drowsiness (up to 50%)•Dizziness (up to 12%)•Runny nose, sore throat, and other symptoms of a respiratory infection (up to 10%)•Extreme tiredness (up to 9%)•Poor movement control, clumsiness (up to 9%)•Depression (up to 8%)Warnings of Clobazam vs. Clonazepam
Common Side Effects for•Serious risks when used with opioids•Potential for misuse, addiction, and withdrawal•Extreme sleepiness or tiredness, leading to trouble with concentration•Serious skin reactions•Suicidal thoughts or behavior•Side effects in newborn babies when used during pregnancyCommon Side Effects for•Sedation and difficulty breathing•Potential for misuse, addiction, dependence, and withdrawal•Suicidal thoughts or behaviors•Effect on driving and concentration•Harm to babies•Worsening of seizuresPrices with our coupons for Clobazam vs. Clonazepam
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