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Clotrimazole Non-Prescription Coupon - Clotrimazole Non-Prescription 15g of 1% tube of cream

clotrimazole non-prescription

Generic
Used for Yeast Infection, Athlete's Foot, Ringworm, Jock Itch
Used for Yeast Infection, Athlete's Foot, Ringworm, Jock Itch

Clotrimazole is an antifungal cream that's placed inside the vagina or onto the surrounding skin. It's used to treat vaginal yeast infections. This medication also helps relieve related symptoms, like itching, burning, and discomfort. Clotrimazole vaginal cream comes in 3-day and 7-day treatment courses, both of which are available over the counter as a lower-cost generic medication. Possible side effects of this vaginal cream include vaginal irritation, itching, and burning.

Reviewed by:
reviewer
Sarah Lobello Pearson, PharmD
reviewer
Kristianne Hannemann, PharmD
Last reviewed on May 14, 2024
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageCostContraindicationsAlternativesImagesReferencesPricesMedicare
basics-icon

What is Clotrimazole?

What is Clotrimazole used for?

How Clotrimazole works

Clotrimazole is an antifungal medication. It works by damaging the protective covering around fungal (yeast) cells so that they can't survive. The medication also slows down fungal growth. This helps treat vaginal yeast infections and relieve related symptoms.

Are you looking for information on clotrimazole (Lotrimin AF) for fungal skin infections or clotrimazole lozenge for oral thrush instead?
When does Clotrimazole start working?
Time passed since treatment started:
HOURS
DAYS
WEEKS
MONTHS
Full effect

Drug Facts

Common BrandsGyne-Lotrimin (brand name no longer available)
Drug ClassAntifungal
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityOver-the-counter
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Avg retail price
$25.71(save 75.75%)
GoodRx discount
$6.24
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basics-icon

What are the side effects of Clotrimazole?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Burning feeling in the vagina or in the area around the opening of the vagina (less than 10%)

Other Side Effects

Source: DailyMed

The following side effects have also been reported

Side effects that you should report to your care team as soon as possible:

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

  • Vaginal irritation at application site
pros-and-cons

Pros and cons of Clotrimazole

thumbs-up

Pros

Can treat most vaginal yeast infections in 3 or 7 days, depending on the strength of the cream you have

Only need to use once a day (for treating vaginal yeast infection)

Available over the counter as a lower-cost generic

thumbs-down

Cons

Can leak out after inserting into the vagina, which can be messy or cause discomfort

Can cause vaginal burning or irritation

Not recommended to have vaginal sex during treatment

pharmacist-tips

Pharmacist tips for Clotrimazole

pharmacist

  • Only use clotrimazole vaginal cream on the inside of the vagina or on the surface of the surrounding skin. Contact a Poison Control Center (1-800-222-1222) if someone accidentally swallows clotrimazole.

    • Apply clotrimazole inside the vagina once a day at bedtime. Using it at bedtime helps lessen the amount of leakage since you'll be lying down. It can be helpful to wear a thin underwear liner after you insert clotrimazole into your vagina to protect your clothing from leakage.

      • Use clotrimazole vaginal cream for the full 3 or 7 days, depending on which treatment course you have, even if you start feeling better. This makes sure your yeast infection is completely treated.

        • Avoid using other vaginal products while you're using clotrimazole. Tampons can absorb some of the medication. Clotrimazole can also sometimes damage condoms and diaphragms and cause them to work less well.

          • It isn't recommended to have vaginal sex while you're using clotrimazole. Having a vaginal yeast infection can make sex painful, and it's even possible to pass a yeast infection to your sexual partner.

            • Contact your gynecologist or primary care provider if your symptoms don't get better after 3 days of treatment. Also call them if you're still having vaginal itching, irritation, burning, or discharge after 7 days of treatment with clotrimazole. There might be another medical condition that's causing your symptoms.

              • Stop using clotrimazole and get medical attention if you have a rash, fever, chills, stomach pain, nausea, vomiting or if you notice a foul-smelling discharge from your vagina. You'll probably need to get examined so you can get the most appropriate care.

                • Talk to your gynecologist or primary care provider if you have vaginal yeast infections often or if you have vaginal symptoms like itching and discomfort for the first time. They might recommend a different treatment for you instead of clotrimazole.

                  • Check the expiration date on the tube of clotrimazole vaginal cream. Don't use the medication if it's past the expiration date since it might not work as well for your vaginal yeast infection.

                    Tips on how to use clotrimazole vaginal cream:

                    • Attach the open end of the applicator to the tip of the tube of cream. Gently squeeze the tube until the applicator is full or is filled to the marked line with medication.

                      • Gently insert the open end of the applicator as far as it will comfortably go into your vagina. Then, push down on the plunger to get the medication into your vagina. Remove the applicator, and throw it away or wash it with soap and warm water if it's reusable.

                        • Wash your hands after each time you use clotrimazole vaginal cream.

                          • You can squeeze a small amount of clotrimazole onto your finger and spread it on the irritated skin around your vagina. Apply once or twice daily for up to 7 days to help with itching and irritation in the area.

                            faqs

                            Frequently asked questions about Clotrimazole

                            Is clotrimazole a steroid?
                            No. Clotrimazole isn't a steroid. It's an antifungal medication, which means that it treats fungal infections. The clotrimazole vaginal cream is inserted into the vagina to treat vaginal yeast infections.
                            Is clotrimazole an antibiotic?
                            No. Antibiotics are medications that treat infections caused by bacteria. Clotrimazole is an antifungal medication that kills a type of fungus.
                            Is clotrimazole over the counter?
                            Yes. Clotrimazole is available over the counter, and it comes in two different strengths: 1% and 2%. Depending on the strength, the number of days that you need to use clotrimazole is different. The 1% cream is a 7-day treatment, whereas the 2% cream is a 3-day treatment. Be sure to read the instructions provided in the product packaging since they can be different depending on which product you have. Also, make sure your product is for vaginal use only since there are other clotrimazole products sold over the counter for fungal skin infections.
                            How well does clotrimazole work in treating yeast infection?
                            Clotrimazole vaginal cream generally works well for treating vaginal yeast infections and relieving related symptoms. In a small study of people who used clotrimazole 1% vaginal cream for 7 days, up to 84% of the vaginal yeast infections were cured. Speak with your gynecologist or primary care provider if you still have symptoms after you finish your entire course of clotrimazole vaginal cream.
                            Can you use clotrimazole vaginal cream for yeast infections while on your period?
                            Yes, you can use clotrimazole while you're on your period. Since tampons might absorb some of the medication, consider using a sanitary pad or period underwear while you're treating your yeast infection. It's important to change these feminine products regularly during your period.
                            Can I use clotrimazole athlete's foot cream for yeast infection?
                            No. Don't treat your vaginal yeast infection with clotrimazole cream (Lotrimin AF) that's specifically meant for athlete's foot, ringworm, or jock itch. Don't put clotrimazole cream that's used for these fungal skin infections inside of the vagina or on the outside skin of the vagina. It's not recommended to use other clotrimazole products in the vagina unless the package specifically says it's for vaginal use. Carefully read the package label to see whether the clotrimazole cream can be used in or around the vagina. Ask a pharmacist if you're not sure.
                            How long does clotrimazole take to work?
                            You might start to notice an improvement in your vaginal yeast infection symptoms within the first 3 days of using clotrimazole. Contact your gynecologist or primary care provider for further evaluation if you still have vaginal yeast infection symptoms after completing a 3-day or 7-day treatment of clotrimazole.
                            Is clotrimazole safe in pregnancy?
                            Studies showed that clotrimazole vaginal cream is safe to use during the second and third trimesters of pregnancy. But ask your obstetrician-gynecologist (OB-GYN) or primary care provider if you can use clotrimazole during your first trimester; the vaginal cream hasn't been well studied in this stage of pregnancy so it's typically used when the benefits clearly outweigh the risks. In general, it's best to check with your OB-GYN or primary care provider before you use any over-the-counter medications like clotrimazole vaginal cream to make sure it's safe for you to use if you’re pregnant.
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                            What are the risks and warnings for Clotrimazole?

                            Clotrimazole can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

                            risk-warning

                            Might not be appropriate for undiagnosed vaginal symptoms

                            Don't use clotrimazole if you've never been diagnosed with a vaginal yeast infection by a healthcare professional before and you're having vaginal itching and discomfort for the first time. Check with your gynecologist or primary care provider first so they can make sure your symptoms are caused by a yeast infection and that this medication is appropriate for you to use.

                            risk-warning

                            Contact a healthcare professional for frequent or severe vaginal symptoms

                            • Risk factors: Previous exposure to the human immunodeficiency virus (HIV)

                              You should speak with your gynecologist or primary care provider before you use clotrimazole if you have frequent vaginal yeast infections (e.g., once every month, 3 infections in 6 months). Also contact them if you have symptoms like fever, chills, nausea, vomiting, lower back or stomach pain, or foul-smelling vaginal discharge in addition to your vaginal symptoms. Your gynecologist or primary care provider can find out whether you have a more serious medical condition that could be causing your infections or symptoms.

                              dosage

                              Clotrimazole dosage forms

                              The average cost for 2 tubes of 15g of 1% of Clotrimazole is $14.99 with a free GoodRx coupon. This is 41.7% off the average retail price of $25.71.
                              bottle of topical solution
                              Bottle of topical solution
                              DosageQuantityPrice as low asPrice per unit
                              10ml of 1%1 bottle$14.56$14.56
                              tube of cream
                              Tube of cream
                              DosageQuantityPrice as low asPrice per unit
                              15g of 1%2 tubes$14.99$7.50
                              28g of 1%1 tube$9.15$9.15
                              30g of 1%1 tube$6.43$6.43
                              45g of 1%1 tube$7.08$7.08
                              21g of 2%1 tube$6.24$6.24

                              Typical dosing for Clotrimazole

                              People age 12 years and older:

                              • Treatment of a vaginal yeast infection

                                • Clotrimazole 1%: Insert one applicatorful (50 mg) into the vagina once daily at bedtime for 7 days in a row.

                                • Clotrimazole 2%: Insert one applicatorful (100 mg) into the vagina once daily at bedtime for 3 days in a row.

                              • Relief of itching or irritation caused by a vaginal yeast infection

                                • Clotrimazole 1% and 2%: Place a small amount of cream onto your fingertip. Apply the cream onto the skin on the outside of the vagina twice daily for up to 7 days as needed.

                              Children under 12 years old: Check with your child’s pediatrician.

                              drug-cost

                              How much does Clotrimazole cost?

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                              contraindications-icon

                              Clotrimazole contraindications

                              Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Clotrimazole will not be safe for you to take.

                              • Never been diagnosed with a vaginal yeast infection before

                              alternatives

                              What are alternatives to Clotrimazole?

                              There are a number of medications that your doctor can prescribe in place of Clotrimazole. Compare a few possible alternatives below.
                              Clotrimazole
                              Used for:
                              $6.24 Lowest GoodRx priceView Prices
                              Monistat (miconazole)
                              Used for:

                              • Treatment of vaginal yeast infection

                              • Relief of vaginal yeast infection symptoms (itching and irritation outside of the vagina)

                              $6.07 Lowest GoodRx priceView Prices
                              Terconazole
                              Used for:
                              $16.26 Lowest GoodRx priceView Prices
                              images

                              Clotrimazole images

                              This medicine is Colorless Tube Of Cream.
                              white - Athlete's Foot 1% Topical Cream
                              This medicine is White Tube Of Cream.white - Athlete's Foot 1% Topical Cream
                              This medicine is Colorless Tube Of Cream.

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                              References

                              Best studies we found

                              AmerisourceBergen. (2020). Good Neighbor Pharmacy Clotrimazole 3- clotrimazole cream [package insert]. DailyMed.

                              H2-Pharma, LLC. (2023). Clotrimazole cream [package insert]. DailyMed.

                              Khatter, N. J., et al. (2023). Clotrimazole. StatPearls.

                              View All References (4)

                              Lebherz, T. B., et al. (1983). A comparison of the efficacy of two vaginal creams for vulvovaginal candidiasis, and correlations with the presence of Candida species in the perianal area and oral contraceptive use. Clinical Therapeutics.

                              Office on Women’s Health. (2021). Vaginal yeast infections.

                              SafeMedication. (n.d.). How to use vaginal tablets, suppositories, and creams.

                              Schering Plough Healthcare Products Inc. (2010). Gyne-Lotrimin [package insert]. U.S. Food and Drug Administration.

                              GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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