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Compare Beyfortus vs. Synagis

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Beyfortus (nirsevimab)
    Synagis (palivizumab)
  • Beyfortus (nirsevimab)
    Synagis (palivizumab)

  • Summary of Beyfortus vs. Synagis

    Summary for Monoclonal antibody
    Prescription only

    Beyfortus (nirsevimab or nirsevimab-alip) is an injection given to babies and children up to 24 months old. It's used to prevent them from getting very sick from respiratory syncytial virus (RSV). It's not an RSV vaccine. Instead, it's a monoclonal antibody that gives protection against the virus for a short time. Beyfortus (nirsevimab) is now part of the CDC Child Immunization Schedule. The usual dosage is 1 to 2 injections into the muscle during or at the start of the RSV season. It's well-tolerated with only a few side effects.

    Summary for Monoclonal antibody
    Prescription only

    Synagis (palivizumab) is a monoclonal antibody. It's given to prevent serious respiratory syncytial virus (RSV) infections in infants and young children who are at high risk for severe illness. Synagis (palivizumab) is injected into the muscle monthly, starting right before and continuing throughout the RSV season. Some of the more common side effects of this medication include fever and rash.

  • Indications of Beyfortus vs. Synagis

    Indications for
    •Prevention of respiratory syncytial virus (RSV) in young children of certain ages
    •Newborns and infants born during or entering their first RSV season
    •Children up to 24 months old at risk of severe RSV illness through their second RSV season
    Indications for

    Prevention of serious respiratory syncytial virus (RSV) infections for:

    •Babies born premature and are 6 months or younger at the start of RSV season
    •Children diagnosed with bronchopulmonary dysplasia (BPD) within the last 6 months, and are 2 years or younger at the start of RSV season
    •Children with congenital heart disease (CHD) and are 2 years or younger at the start of RSV season

  • Pros and Cons of Beyfortus vs. Synagis

    Pros and Const for Monoclonal antibody
    Pros
    •Given during one medical visit
    •Can lower the risk of severe RSV-related illness by about 70% in full-term and premature babies
    •Not many side effects
    Cons
    •Injection can be uncomfortable
    •Protection might only last for about 5 months
    •Not known if it's safe or if it works well for children older than 24 months
    Pros and Const for Monoclonal antibody
    Pros
    •Lowers the risk of serious RSV illness
    •Not known to affect how well vaccines work
    Cons
    •Given monthly during RSV season, instead of once a year, like its alternative
    •Can't treat RSV infections (only prevents)

  • Common Side Effects of Beyfortus vs. Synagis

    Common Side Effects for
    •Side effects aren't common. See Other Side Effects.
    Common Side Effects for
    •Fever (27%)
    •Rash (12%)

  • Warnings of Beyfortus vs. Synagis

    Common Side Effects for
    •Severe allergic reaction
    •Caution use in children with bleeding problems
    Common Side Effects for
    •Severe allergic reaction
    •Bleeding problems
    •Not for treatment for RSV

  • Prices with our coupons for Beyfortus vs. Synagis

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    Learn more about Synagis

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