Pertzye vs. Creon for Pancreatic Insufficiency: Important Differences and Potential Risks.

Pertzye

(pancrelipase)

Creon

(pancrelipase)

Summary for Pertzye

Prescription only

Pertzye (pancrelipase) is a prescription medication used to treat children and adults with exocrine pancreatic insufficiency (EPI), a condition where the pancreas doesn’t make enough enzymes to digest food. It contains pancreatic enzymes that help break down fats, carbohydrates, and proteins. The medication comes as a capsule that you take by mouth with every meal and snack, and your dose is based on your weight, age, and fat intake. Common side effects include diarrhea, indigestion, and cough. There's currently not a generic version available.

Indications for Pertzye

Exocrine pancreatic insufficiency

Pros and Cons for Pertzye

Pros

Capsules can be opened up and mixed with applesauce
Safe for children and infants
Comes in multiple strengths
No known interactions with other medications

Cons

Must be taken with every meal and snack
Might not be safe to take for people with pork allergy
Can cause stomach pain and vomiting
Dose adjustment can take a while

Common Side Effects for Pertzye

Diarrhea (10%)
Indigestion (10%)
Cough (10%)

Warnings for Pertzye

Scarring in the colon (fibrosing colonopathy)
Mouth irritation
High uric acid levels
Possible risk of infection
Severe allergic reaction

Summary for Creon

Prescription only

Creon (pancrelipase) is a prescription medication that contains pancreatic enzymes to help you digest food if your body doesn't make enough of them. It's used in both children and adults to treat exocrine pancreatic insufficiency (EPI). The medication comes as a pill that you take by mouth with every meal and snack to help break down food. The dose depends on your weight, age, and how much fat you eat, and it might be adjusted over time. Common side effects include cough, stomach pain, and vomiting.

Indications for Creon

Exocrine pancreatic insufficiency (EPI)

Pros and Cons for Creon

Pros

Capsules can be opened up and mixed with certain soft foods
Safe for children and infants
Comes in multiple strengths
No known interactions with other medications

Cons

Must be taken with every meal and snack
Might not be safe to take for people with pork allergy
Can cause stomach pain and vomiting
Dose adjustment can take a while

Common Side Effects for Creon

Adults and children 7 years and older with cystic fibrosis:

Vomiting (6%)
Dizziness (4%)
Cough (4%)

Children ages 4 months to 6 years old with cystic fibrosis:

Vomiting (6%)
Irritability (6%)
Reduced appetite (6%)

Adults with chronic pancreatitis or pancreas removal surgery:

High blood sugar (8%)
Low blood sugar (4%)
Stomach pain (4%)
Abnormal stool (4%)
Passing gas (4%)
Frequent bowel movements (4%)
Common cold symptoms (4%)

Warnings for Creon

Scarring in the colon (fibrosing colonopathy)
Mouth irritation
High uric acid levels
Possible risk of infection
Severe allergic reactions

Prices with our coupons for Pertzye vs. Creon

Pertzye100 capsules / 4000 units

$187.10$226.53

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Creon100 capsules / 36000 units

$1,278.11$1,655.41

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Pertzye vs. Creon

Pertzye

Creon

Summary for Pertzye

Indications for Pertzye

Pros and Cons for Pertzye

Pros

Cons

Common Side Effects for Pertzye

Warnings for Pertzye

Summary for Creon

Indications for Creon

Pros and Cons for Creon

Pros

Cons

Common Side Effects for Creon

Warnings for Creon

Prices with our coupons for Pertzye vs. Creon

Browse medications by letter

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Pertzye

Creon

Summary for Pertzye

Indications for Pertzye

Pros and Cons for Pertzye

Pros

Cons

Common Side Effects for Pertzye

Warnings for Pertzye

Summary for Creon

Indications for Creon

Pros and Cons for Creon

Pros

Cons

Common Side Effects for Creon

Warnings for Creon