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INFed vs. Venofer

INFeD (iron dextran) is an injectable iron supplement for people ages 4 months and older who have iron deficiency (low iron levels), including those with iron-deficiency anemia (low red blood cell count due to low iron levels). It's used when people have already tried or can't take oral iron supplements. INFeD (iron dextran) is given as an injection either into the vein (IV) or into the muscle (IM). Side effects include hypersensitivity (allergic) reactions, like dizziness, nausea, and chest pain.

• Iron deficiency (including iron-deficiency anemia) in people who either have already tried or can't take oral iron supplements

• Nausea
• Vomiting
• Diarrhea
• Stomach pain
• Chest pain or chest tightness
• Back pain
• Difficulty breathing
• Headache
• Dizziness
• Flushing
• Skin rash or itch

• Serious allergic reactions
• Too much iron in the body

Venofer (iron sucrose) is an injectable iron supplement that's used to treat iron-deficiency anemia (IDA) in adults and children with chronic kidney disease (CKD). Venofer (iron sucrose) is given by a healthcare professional as an injection or infusion through the veins (IV). The dose depends on your age, your need for dialysis, and the type of dialysis you're having (either hemodialysis or peritoneal dialysis). Side effects include low blood pressure, headache, and nausea.

• Iron-deficiency anemia (low red blood cell count due to low iron levels) in people with chronic kidney disease

Adults with CKD on hemodialysis:

• Low blood pressure (39%)
• Muscle cramps (29%)
• Nausea (15%)
• Headache (13%)
• Vomiting (9%)
• High blood pressure (7%)
• Dizziness (7%)
• Diarrhea (5%)

Children 2 years and older with CKD:

• Headache (6%)
• Viral respiratory tract infection (e.g., common cold; 4%)
• Swelling in stomach area (4%)
• Vomiting (4%)
• Fever (4%)
• Dizziness (4%)
• Cough (4%)

• Serious allergic reactions
• Low blood pressure
• Too much iron in the body