What is Aqvesme?

They need to know if you have any of these conditions:

• Liver disease
• An unusual or allergic reaction to mitapivat, other medications, foods, dyes, or preservatives
• Pregnant or trying to get pregnant
• Breastfeeding

Take this medication by mouth. Take it as directed on the prescription label at the same time every day. Do not cut, crush, or chew this medication. Swallow the tablets whole. Keep taking it unless your care team tells you to stop.

Talk to your care team about the use of this medication in children. Special care may be needed.

If you miss a dose, take it as soon as you can, unless it is more than 4 hours late. If it is more than 4 hours late, skip the missed dose. Take the next dose at the normal time.

Keep out of the reach of children and pets.

Refrigeration (preferred): Store in the refrigerator. Keep this medication in the original carton. Get rid of any unused medication after the expiration date.

Room temperature: This medication may be stored at room temperature between 20 and 25 degrees C (68 and 77 degrees F) for up to 3 months. Keep it in the original carton. Get rid of any unused medication after 3 months or after it expires, whichever is first.

To get rid of medications that are no longer needed or have expired:

• Take the medication to a take-back program. Check with your pharmacy or law enforcement to find a location.
• If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, empty the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.