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Zyclara Coupon - Zyclara 7.5g of 3.75% cream pump
IMIQUIMOD cream is used to treat external genital or anal warts. It is also used to treat other skin conditions such as actinic keratosis and certain types of skin cancer. Compare immune response modifiers.
Prescription Settings
cream pump
7.5g of 3.75%
1 cream pump
Zyclara Coupon - Zyclara 7.5g of 3.75% cream pump
cream pump
7.5g of 3.75%
1 cream pump

Zyclara Side Effects

What should I watch for?

Visit your health care professional for regular checks on your progress.

Do not use this medicine until the skin has healed from any other drug (example: podofilox or podophyllin resin) or surgical skin treatment.

Females should receive regular pelvic exams while being treated for genital warts. Most patients see improvement within 4 weeks. It may take up to 16 weeks to see a full clearing of the warts. This medicine is not a cure. New warts may develop during or after treatment. Avoid sexual (genital, anal, oral) contact while the cream is on the skin. If warts are visible in the genital area, sexual contact should be avoided until the warts are treated. The use of latex condoms during sexual contact may reduce, but not entirely prevent, infecting others. This medicine may weaken condoms, diaphragms, cervical caps or other barrier devices and make them less effective as birth control. Do not cover the treated area with an airtight bandage. Cotton gauze dressings can be used. Cotton underwear can be worn after using this medicine on the genital or anal area.

Actinic keratoses that were not seen before may appear during treatment and may later go away. The treatment area and surrounding area may lighten or darken after treatment with this medicine. These skin color changes may be permanent in some patients.

If you experience a skin reaction at the treatment site that interferes or prevents you from doing any daily activity, contact your health care provider. You may need a rest period from treatment. Treatment may be restarted once the reaction has gotten better as recommended by your doctor or health care professional.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.


Common and Rare Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Blisters on the skin

body aches or pain



difficulty with breathing

ear congestion

itching in the genital or other skin areas

loss of voice

open sores or scabs on the skin

pain or tenderness around the eyes and cheekbones

redness of the skin (severe)


shortness of breath or troubled breathing

skin rash


sore throat

stuffy or runny nose

tightness of the chest or wheezing

unusual tiredness or weakness

Less common

Abdominal or stomach pain

ankle, knee, or great toe joint pain

bladder pain

bloody or cloudy urine

blurred vision

chest pain

cold flu-like symptoms

difficult, burning, or painful urination



fast or irregular heartbeat

frequent urge to urinate


joint stiffness or swelling

lower back or side pain

lump in the abdomen or stomach


persistent non-healing sore

pink growth on the skin

pounding in the ears

reddish patch or irritated area

severe headache

shiny bump on the skin

slow or fast heartbeat

swollen, painful, or tender lymph glands in the neck, armpit, or groin

white, yellow or waxy scar-like area

Incidence not known

Blue lips and fingernails


coughing that sometimes produces a pink frothy sputum

dilated neck veins

extreme fatigue

fast, irregular, or pounding heartbeat


irregular breathing

nausea or vomiting

pain in the shoulders, arms, jaw, or neck

slurred speech

sudden and severe inability to speak



swelling of the face, fingers, feet, or lower legs

temporary blindness

weakness in the arm or leg on one side of the body

weight gain

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose


dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Burning or stinging of the skin (mild)

flaking of the skin

mild headache

pain, soreness, or tenderness of the skin (mild)


redness of the skin (mild)

swelling at place of application

Less common

Back pain

lightening of the treated skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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