Specialty Drug


INCOBOTULINUMTOXINA is a neuro-muscular blocker. This medicine is used to treat eyelid, neck muscle, and hand and arm muscle spasms. It is also used to decrease drooling and to treat frown lines on the face. Compare acetylcholine release inhibitors.

Xeomin Side Effects

What should I watch for?

Visit your doctor for regular check ups.

This medicine will cause weakness in the muscle where it is injected. Tell your doctor if you feel unusually weak in other muscles. Get medical help right away if you have problems with breathing, swallowing, or talking.

This medicine contains albumin from human blood. It may be possible to pass an infection in this medicine, but no cases have been reported. Talk to your doctor about the risks and benefits of this medicine.

If your activities have been limited by your condition, go back to your regular routine slowly after treatment with this medicine.

You may get muscle weakness, blurred vision, or drooping eyelids. If this happens, do not drive, use machinery, or do other dangerous activities.


Common and Rare Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common—for cervical dystonia

Difficulty with swallowing

muscle or bone pain

muscle weakness

pain in the neck

More common—for blepharospasm

Dry eyes

Rare—for glabellar lines

Itching, pain, redness, or swelling at the injection site

pain in the face

swelling of the eyelids

Incidence not known

Changes in patterns and rhythms of speech

fast heartbeat


hives, itching, or rash



joint pain, stiffness, or swelling

muscle spasm

pain at the injection site

redness of the skin

slurred speech

swelling of the eyes or eyelids

swelling of the face, lips, hands, or feet

tightness in the chest

trouble with speaking

troubled breathing or swallowing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common—for cervical dystonia



lower back or side pain

painful or difficult urination

More common—for blepharospasm

Blurred vision


drooping upper eyelids

dry mouth


Less common—for blepharospasm

Difficult or labored breathing

muscle aches


sore throat

stuffy or runny nose

unusual tiredness or weakness

Less common—for upper limb spasticity

Dry mouth



muscle aches

sore throat

stuffy or runny nose

unusual tiredness or weakness

Rare—for glabellar lines

Drooping of the eyelids

increased blinking

twitching of the eyelids

Incidence not known

Difficulty with moving

joint pain

muscle aching or cramping

muscle pains or stiffness


painful blisters on the trunk of the body

swollen joints

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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