What should I watch for?
Visit your doctor for checks on your progress. This drug may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.
In some cases, you may be given additional medicines to help with side effects. Follow all directions for their use.
Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This drug decreases your body's ability to fight infections. Try to avoid being around people who are sick.
This medicine may increase your risk to bruise or bleed. Call your doctor or health care professional if you notice any unusual bleeding.
Be careful brushing and flossing your teeth or using a toothpick because you may get an infection or bleed more easily. If you have any dental work done, tell your dentist you are receiving this medicine.
Do not become pregnant while taking this medicine or for 6 months after stopping it. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine or for 2 weeks after stopping it.
Men are advised not to father a child while taking this medicine or for 3 months after stopping it.
This medicine may make it more difficult to get pregnant or father a child. Talk with your doctor or health care professional if you are concerned about your fertility.
Common and Rare Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Abdominal or stomach pain
loss of fingerprints
numbness, pain, tingling, or other unusual sensations in the palms of the hands or bottoms of the feet
pain, blistering, peeling, redness, or swelling of the palms of the hands or bottoms of the feet
pain, redness, swelling, sores, or ulcers in your mouth or on your lips
unusual tiredness or weakness
Less common or rare
Abdominal or stomach cramping or pain (severe)
bleeding and bruising
blood in the urine or stools
bloody or black, tarry stools
burning, dry, or itching eyes
clumsiness or unsteadiness
cough producing mucus
coughing or spitting up blood
decreased frequency or amount of urine
difficulty with breathing
difficulty with swallowing or pain in the back of throat or chest when swallowing
discharge from the eyes
eye redness, irritation, or pain
fast or irregular heartbeat
fever or chills
headache, sudden and severe
heavier menstrual periods
hot, red skin on the feet or legs
inability to speak
increased menstrual flow or vaginal bleeding
itching in the genital or other skin areas
loss of consciousness
muscle aches or cramps
numbness or tingling in the hands, feet, or lips
painful or difficult urination (accompanied by fever or chills)
painful, swollen feet or legs
pain, tenderness, or swelling in the upper abdominal or stomach area
pinpoint red spots on the skin
problems with coordination
prolonged bleeding from cuts
rapid, shallow breathing
red or dark brown urine
redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid
skin rash or itching
slow or irregular heartbeat
sores, ulcers, or white spots on the lips or in the mouth
stomach bloating, burning, or cramping
swelling of the face, fingers, feet, or lower legs
swelling of the lymph nodes
tiredness or weakness
trouble with speaking
troubled breathing or tightness in the chest
unusual bleeding or bruising
unusual lump or swelling in the chest
vomiting blood or material that looks like coffee grounds
weakness in the arm or leg on one side of the body, sudden and severe
weight gain or loss
white patches in the mouth or throat or on the tongue
white patches with diaper rash
yellow eyes or skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Burning, crawling, itching, numbness, prickling, “pins and needles”, or tingling feelings
changes or discoloration in the fingernails or toenails
difficulty with moving
increased sensitivity of the skin to sunlight
pain and redness of the skin at the place of x-ray treatment
pain in the joints or limbs
red, sore eyes
change in color of treated skin
difficulty with walking
feeling of constant movement of self or surroundings
feeling sad or empty
full or bloated feeling or pressure in the stomach
general feeling of discomfort or illness
lack of appetite
loss of interest or pleasure
pain in the rectum
pain, swelling, or redness in the joints
passing less gas
rough, scratchy sound to voice
sensation of spinning
shakiness in the legs, arms, hands, or feet
sores on the skin
swelling of abdominal or stomach area
tremor or shaking of the hands or feet
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.