What should I watch for?
This medicine does not prevent heart attack or stroke. In fact, this medicine may increase the chance of a heart attack or stroke. The chance may increase with longer use of this medicine and in people who have heart disease. If you take aspirin to prevent heart attack or stroke, talk with your doctor or health care professional.
Do not take medicines such as ibuprofen and naproxen with this medicine. Side effects such as stomach upset, nausea, or ulcers may be more likely to occur. Many medicines available without a prescription should not be taken with this medicine.
This medicine can cause ulcers and bleeding in the stomach and intestines at any time during treatment. Do not smoke cigarettes or drink alcohol. These increase irritation to your stomach and can make it more susceptible to damage from this medicine. Ulcers and bleeding can happen without warning symptoms and can cause death.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.
This medicine can cause you to bleed more easily. Try to avoid damage to your teeth and gums when you brush or floss your teeth.
Common and Rare Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Swelling of face, fingers, lower legs, ankles, and/or feet
weight gain (unusual)
Bruising (not at place of injection)
skin rash or itching
small, red spots on skin
sores, ulcers, or white spots on lips or in mouth
Abdominal or stomach pain, cramping, or burning that is severe
bleeding from the rectum or bloody or black, tarry stools
bloody or cloudy urine
blue lips and fingernails
blurred vision of other vision change
burning, red, tender, thick, scaly, or peeling skin
cough or hoarseness
decrease in amount of urine that is sudden
fast, irregular, noisy, or troubled breathing
fever with severe headache, drowsiness, confusion, and stiff neck or back
hallucinations (seeing, hearing, or feeling things that are not there)
increase in amount of urine or urinating often
loss of appetite
mood changes or unusual behavior
muscle cramps or pain
pain in lower back and/or side
pain, tenderness, or swelling in the upper stomach area
painful or difficult urination
puffiness or swelling of the eyelids or eyes
ringing or buzzing in ears
shortness of breath
swollen or painful glands
thirst that continues
tightness in the chest with or without wheezing
unusual tiredness or weakness
vomiting of blood or material that looks like coffee grounds
yellow eyes or skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Abdominal or stomach pain (mild or moderate)
bruising at place of injection
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.