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Specialty Drug

TEMSIROLIMUS is a drug that alters immune system response in the body. It is used to treat renal cell cancer. Compare kinase inhibitors.

Prescription Settings

Temsirolimus Side Effects

What should I watch for?

Visit your doctor for regular check-ups. you will need important blood work done while you are taking this medicine.

This drug may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.

Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This drug decreases your body's ability to fight infections. Try to avoid being around people who are sick.

This medicine may increase your risk to bruise or bleed. Call your doctor or health care professional if you notice any unusual bleeding.

Be careful brushing and flossing your teeth or using a toothpick because you may get an infection or bleed more easily. If you have any dental work done, tell your dentist you are receiving this medicine.

Avoid taking products that contain aspirin, acetaminophen, ibuprofen, naproxen, or ketoprofen unless instructed by your doctor. These medicines may hide a fever.

Do not become pregnant while taking this medicine or for 3 months after stopping it. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. Men should not father a child while taking this medicine and for 3 months after stopping it. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine or for 3 weeks after the last dose.

Common and Rare Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

Bladder pain

bloody nose

bloody or cloudy urine

body aches or pain

blurred vision

chest pain

chills

congestion

cough

cracked lips

diarrhea

difficult or labored breathing

difficult, burning, or painful urination

difficulty with swallowing

dizziness

dryness or soreness of the throat

ear congestion

fever

frequent urge to urinate

headache

hoarseness

joint or muscle pain

lack or loss of strength

loss of voice

lower back or side pain

nasal congestion

nausea

nervousness

numbness or tingling of the face, hands, or feet

pounding in the ears

runny nose

skin rash

slow or fast heartbeat

sneezing

sores, ulcers, or white spots on the lips, tongue, or inside the mouth

sore throat

stomach pain

stuffy or runny nose

swelling of the hands, ankles, feet, or lower legs

swelling or puffiness of the face

tender, swollen glands in the neck

tightness in the chest

voice changes

vomiting

Less common

Black, tarry stools

bloody stools

changes in skin color

delayed wound healing

pain, tenderness, or swelling of the foot or leg

seizures

severe vomiting, sometimes with blood

stomach cramp

vomiting of blood or material that looks like coffee grounds

Incidence not known

Blistering, peeling, or loosening of the skin

dark-colored urine

itching

muscle cramps, spasms, or stiffness

pain or redness at the injection site

pale skin at injection site

red skin lesions, often with a purple center

red, irritated eyes

unusual tiredness or weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Back pain

blemishes on the skin

burning, dry, or itching eyes

change in taste

difficulty having a bowel movement

difficulty with moving

discharge or excessive tearing

discoloration of the fingernails or toenails

dry skin

loss of appetite

loss of taste

pimples

redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid

swollen joints

trouble sleeping

weight loss

Less common

Discouragement

feeling sad or empty

irritability

loss of interest or pleasure

tiredness

trouble concentrating

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Other kinase inhibitors

Other Conditions

Renal Cancer

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