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Specialty Drug
SUNITINIB is a medicine that targets proteins in cancer cells and stops the cancer cells from growing. It is used to treat specific digestive tract tumors called GISTs, advanced kidney cancer, and certain pancreatic neuroendocrine tumors. The lowest GoodRx price for the most common version of Sutent is around $14,570.39, 6% off the average retail price of $15,536.73. Compare kinase inhibitors.
Prescription Settings
28 capsules
28 capsules

Sunitinib Side Effects

What should I watch for?

Visit your doctor for regular check ups. Talk to your doctor about any new or unusual health problems. You will need blood work done while you are taking this medicine.

Tell your dentist and dental surgeon that you are taking this medicine. You should not have major dental surgery while on this medicine. See your dentist to have a dental exam and fix any dental problems before starting this medicine. Take good care of your teeth while on this medicine. Make sure you see your dentist for regular follow-up appointments.

Do not become pregnant while taking this medicine or for 4 weeks after stopping it. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. Men should not father a child while taking this medicine and for 7 weeks after stopping it. There is a potential for serious side effects to an unborn child. Men should inform their doctors if they wish to father a child. This medicine may lower sperm counts. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine or for 4 weeks after the last dose.


Common and Rare Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Bleeding gums

bloating or swelling of the face, arms, hands, fingers, lower legs, or feet

blurred vision

chest pain



coughing up blood

cracked lips

decreased urine output and frequency


difficulty with breathing or swallowing

dilated neck veins


dry mouth

extreme tiredness or weakness


fast, slow, or irregular heartbeat



increased menstrual flow or vaginal bleeding

irregular breathing

labored breathing





pounding in the ears

prolonged bleeding from cuts

rapid breathing

rapid weight gain

red or black, tarry stools

red or dark brown urine

sores, ulcers, or white spots on the lips, tongue, or inside the mouth

sunken eyes

swelling or inflammation of the mouth


tightness in the chest

tingling of the hands or feet

troubled breathing

unusual tiredness or weakness

unusual weight gain or loss

wrinkled skin

yellow eyes or skin

Less common

Bleeding from the rectum

bleeding from wounds


depressed mood

dry skin and hair

feeling cold

hair loss

hoarseness or husky voice


loss of appetite

muscle cramps and stiffness


pain in the chest, groin, or legs, especially the calves

pain in the stomach, side, or abdomen, possibly radiating to the back

severe stomach pain

severe, sudden headache

slurred speech

sudden loss of coordination

sudden, severe weakness or numbness in the arm or leg

vision changes


vomiting of blood or material that looks like coffee grounds


Back pain

chest discomfort

cloudy or bloody urine

darkening of the skin


general feeling of tiredness or weakness

irregular or slow heart rate

light-colored stools

mental depression


skin rash

stomach pain, continuing

Incidence not known

Blistering, peeling, or loosening of the skin


dark-colored urine

heavy feeling of the jaw

increased thirst


joint pain, stiffness, or swelling

loosening of a tooth

lower back or side pain

muscle cramps or spasms

muscular pain, tenderness, wasting, or weakness

pain, swelling, or numbness in the mouth or jaw

painful or difficult urination

pale skin

red skin lesions, often with a purple center

sore throat

sudden, severe chest pain

unusual bleeding or bruising

weight gain

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common


blistering, peeling, redness, or swelling of the palms, hands, or bottoms of the feet

change in color of the treated skin

change in taste

difficulty with moving


excess air or gas in the stomach or bowels

feeling of fullness

feeling sad or empty

hair color changes

hair loss or thinning of the hair



lack of appetite

lack or loss of strength

loss of interest or pleasure

muscle aches or pains

numbness, pain, tingling, or unusual sensations in the palms of the hands or bottoms of the feet

pain or burning in the throat

passing gas

stomach discomfort, upset, or pain

swollen joints

trouble concentrating

trouble sleeping

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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