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Itraconazole Coupon - Itraconazole 150ml of 10mg/ml bottle of oral solution

itraconazole oral solution

Generic Sporanox
Used for Nail Fungus, Fungal Infection
Used for Nail Fungus, Fungal Infection

Itraconazole oral solution, also known by its brand name Sporanox, is an azole antifungal used to treat adults with fungal infections in the mouth and throat (oral thrush) and esophagus. You typically swish and swallow the dose once or twice a day on an empty stomach. Itraconazole (Sporanox) oral solution isn't a first-choice treatment option because it can interact with many other medications. It also has rare but serious side effects like heart failure, liver problems, and hearing loss.

Last reviewed on January 12, 2025
basics-icon

What is Itraconazole (Sporanox) oral solution?

What is Itraconazole (Sporanox) oral solution used for?

How Itraconazole (Sporanox) oral solution works

Itraconazole (Sporanox) oral solution is an azole antifungal. It works by stopping the fungus from building its protective covering, which stops it from growing and surviving.

Are you looking for information on itraconazole capsules (Sporanox) instead?
When does Itraconazole (Sporanox) oral solution start working?
Time passed since treatment started:
HOURS
DAYS
WEEKS
MONTHS
Initial effect
Full effect

Drug Facts

Common BrandsSporanox
Drug ClassAntifungal
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityPrescription only
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Avg retail price
$272.38(save 86.91%)
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$35.65
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What are the side effects of Itraconazole (Sporanox) oral solution?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Nausea (11%)
  • Diarrhea (11%)
  • Vomiting (7%)
  • Fever (7%)
  • Stomach pain (6%)

Other Side Effects

  • Rash
  • Constipation
  • Tiredness
  • Coughing
  • Dizziness
  • Sweating
  • Headache
  • Trouble breathing
  • Chest pain

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Congestive heart failure (CHF): trouble breathing, swelling in the arms and legs, sudden weight gain, tiredness, dizziness, lightheadedness, feeling your heart beat very fast
  • Abnormal heart rhythm: dizziness, feeling faint, lightheaded, feeling your heart beating fast
  • Liver damage: nausea, vomiting, unusual tiredness, yellowing of the skin or whites of the eyes (jaundice), dark-colored urine, pale-colored stools
  • Hearing loss: muffled hearing, difficulty understanding speech
When do Itraconazole (Sporanox) oral solution possible side effects begin and end?
Time passed since treatment started:
HOURS
DAYS
WEEKS
MONTHS
Hearing loss
Liver damage
Seek immediate medical care if you experience this side effect.

Source: DailyMed

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Decreased urine output

dry mouth

fever

increased thirst

irregular heartbeat

loss of appetite

mood changes

muscle pain or cramps

nausea

numbness or tingling in the hands, feet, or lips

seizures

trouble breathing

unusual tiredness or weakness

vomiting

Less common

Blurred vision

chest pain

chills

clay-colored stools

cloudy urine

cold sweats

confusion

cough

dark urine

decrease in urine-concentrating ability

diarrhea

dizziness

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

drowsiness

feeling unusually cold

headache

itching, skin rash

light-colored stools

mental changes

muscle cramps in the hands, arms, feet, legs, or face

muscle spasms (tetany) or twitching

nervousness

noisy, rattling breathing

numbness and tingling around the mouth or fingertips

pounding in the ears

shivering

slow, fast, or pounding heartbeat or pulse

sneezing

sore throat

stomach cramps or pain

sweating

swelling of the fingers, hands, feet, or lower legs

tightness in the chest

trembling

troubled breathing at rest

unpleasant breath odor

vomiting of blood

weight gain

yellow eyes or skin

Rare

Black, tarry stools

bleeding gums

blistering, peeling, or loosening of the skin

bloating or swelling of the face, arms, hands, lower legs, or feet

blood in the urine or stools

blue lips and fingernails

burning, crawling, itching, numbness, painful, prickling, "pins and needles", or tingling feelings

continuing ringing or buzzing or other unexplained noise in the ears

coughing that sometimes produces a pink frothy sputum

cracks in the skin

decreased appetite

difficulty with swallowing

dilated neck veins

disturbed color perception

double vision

extreme tiredness or weakness

fast or irregular breathing

feeling of discomfort

general feeling of tiredness or weakness

halos around lights

hearing loss

hives or welts

inflammation of the joints

joint pain

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals

loss of heat from the body

loss of vision

lower back or side pain

night blindness

overbright appearance of lights

painful or difficult urination

pale skin

pinpoint red spots on the skin

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

rapid weight gain

red skin lesions, often with a purple center

red, irritated eyes

red, swollen skin

scaly skin

sores, ulcers, or white spots on the lips or in the mouth

stomach pain, continuing

stomach tenderness

swollen lymph glands

tunnel vision

unsteadiness or awkwardness

unusual bleeding or bruising

unusual weight gain or loss

upper right abdominal or stomach pain

weakness in the arms, hands, legs, or feet

Incidence not known

Bloating

constipation

difficult, fast, noisy breathing

indigestion

loss of bladder control

pains in the stomach, side, or abdomen, possibly radiating to the back

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Decreased interest in sexual intercourse

difficulty having a bowel movement

difficulty with moving

discouragement

feeling of constant movement of self or surroundings

feeling sad or empty

inability to have or keep an erection

irritability

loss in sexual ability, desire, drive, or performance

loss of interest or pleasure

muscle aching or stiffness

pain or tenderness around the eyes and cheekbones

passing of gas

sensation of spinning

sleepiness or unusual drowsiness

soreness of the skin

stomach fullness or discomfort

stuffy or runny nose

trouble concentrating

trouble sleeping

Rare

Belching

change in taste

hair loss or thinning of the hair

heartburn

increased need to urinate

increased sensitivity of the eyes or skin to sunlight

loss of taste

menstrual changes

passing urine more often

redness or other discoloration of the skin

severe sunburn

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Itraconazole (Sporanox) oral solution

thumbs-up

Pros

Taken once to twice per day

Directly treats the infected areas

Good option for people who can't swallow pills

thumbs-down

Cons

Not a first-choice treatment option

Commonly causes nausea, vomiting, and diarrhea

Interacts with many medications

pharmacist-tips

Pharmacist tips for Itraconazole (Sporanox) oral solution

pharmacist
  • It's best if Itraconazole (Sporanox) oral solution is taken on an empty stomach without food. Food reduces how much of the medication your body absorbs, which might make it work less well.

    • Swish Itraconazole (Sporanox) oral solution in your mouth for several seconds before swallowing. Use about 10 mL (2 teaspoonfuls) at a time.

      • Follow your prescriber’s instructions and finish your entire course of Itraconazole (Sporanox) oral solution, even if you feel better. Stopping early might cause the infection to return and become harder to treat.

        • Let your prescriber know if you have heart failure. Itraconazole (Sporanox) oral solution can cause or worsen heart failure. If you start to have trouble breathing, swelling in the arms and legs, sudden weight gain, tiredness, or dizziness, stop taking the medication and contact your prescriber right away.

          • Itraconazole (Sporanox) oral solution can cause vision changes, such as blurry or double vision, and might also cause confusion or drowsiness. Don't drive or operate machinery until you know how this medication affects you.

            • Itraconazole (Sporanox) oral solution interacts with several medications. Make sure to tell your care team about all of the medications you take before and during treatment.

              • Itraconazole (Sporanox) oral solution can cause liver problems. Stop taking the medication right away and contact your prescriber if you notice symptoms such as unusual tiredness, loss of appetite, nausea, vomiting, yellowing of your skin or eyes, dark urine, or pale stools.

                • Be aware that hearing loss can happen while taking Itraconazole (Sporanox) oral solution. In most cases, hearing improves after stopping the medication, but it might remain for some people. Stop taking Itraconazole (Sporanox) oral solution and contact your prescriber if you notice any hearing loss.

                  • Avoid Itraconazole (Sporanox) oral solution during pregnancy, since it can cause severe development problems in babies. If you can get pregnant, use birth control while taking Itraconazole (Sporanox) oral solution and for at least 2 months after treatment.

                    • Tell your prescriber if you're breastfeeding. There aren't any studies to know if Itraconazole (Sporanox) oral solution is safe while nursing. It's often recommended to take another medication or to stop breastfeeding and use formula.

                      faqs

                      Frequently asked questions about Itraconazole (Sporanox) oral solution

                      Is Itraconazole (Sporanox) oral solution an antibiotic?
                      No, Itraconazole (Sporanox) oral solution isn't an antibiotic; it's an antifungal. Antibiotics treat infections caused by bacteria, whereas antifungals treat infections caused by fungi.
                      Is Itraconazole (Sporanox) oral solution a strong inhibitor?
                      Yes, Itraconazole (Sporanox) oral solution is a strong inhibitor CYP3A4, an enzyme (protein) that breaks down many medications. This can cause other medications to build up to unsafe levels, raising your risk for serious side effects. Because of this, [ Itraconazole (Sporanox) oral solution interacts with many medications, including dronedarone, triazolam, felodipine, and simvastatin. Be sure to tell your care team about all the medications you’re taking to make sure they are safe to use together.
                      How long does Itraconazole (Sporanox) oral solution take to work?
                      It depends on your infection. Oral thrush usually clears up within a few days of starting Itraconazole (Sporanox) oral solution. If the infection didn’t respond to fluconazole, it can take about 2 to 4 weeks to see an improvement. For fungal infections in the esophagus, it typically takes at least 3 weeks. Talk to your prescriber if you're concerned with how well Itraconazole (Sporanox) oral solution is working for you.
                      How long can I take Itraconazole (Sporanox) oral solution?
                      In general, you'll take Itraconazole (Sporanox) oral solution for oral thrush for 1 to 2 weeks. If fluconazole didn't work and you're switched to Itraconazole (Sporanox) oral solution, treatment can last 2 to 4 weeks, but could go up to 6 months. For fungal infections in the esophagus, treatment typically lasts at least 5 weeks. Your prescriber will decide how long you need to take Itraconazole (Sporanox) oral solution based on how well it’s working and how severe your infection is. Be sure to take it exactly as prescribed, and ask your prescriber if you’re unsure how long to use it.
                      How long does Itraconazole (Sporanox) oral solution stay in your system?
                      It takes about 3 to 6 days for most of Itraconazole (Sporanox) oral solution to leave your body after a single dose. But it can stay in your system for up to 6 to 9 days as you continue to take the medication. This timeframe is based on the half-life of the medication. Talk with your healthcare team if you have concerns about how long Itraconazole (Sporanox) oral solution might stay in your body.
                      Can you buy Itraconazole (Sporanox) oral solution over the counter?
                      No, Itraconazole (Sporanox) oral solution isn't available over the counter. It's only available by prescription from a healthcare professional.
                      What's the difference between Itraconazole (Sporanox) oral solution and capsules?
                      The Itraconazole (Sporanox) oral solution is a liquid approved to treat oral thrush and fungal infections in the esophagus. The capsules, on the other hand, are approved for treating serious fungal infections throughout the body and fungal nail infections. In addition, Itraconazole (Sporanox) oral solution is taken on an empty stomach, whereas the capsules are taken with food. Lastly, both forms contain different amounts of itraconazole, so they're not interchangeable. Talk to your prescriber if you have questions about the differences between these medications.
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                      warings-icon

                      What are the risks and warnings for Itraconazole (Sporanox) oral solution?

                      Itraconazole (Sporanox) oral solution can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

                      risk-warning

                      Heart failure

                      • Risk factors: History of heart failure or other heart problems | History of chronic obstructive pulmonary disease (COPD) | Kidney problems | Other conditions that cause swelling in the body | Taking calcium channel blockers

                        Itraconazole (Sporanox) oral solution can cause heart failure. Your risk is higher if you have other heart problems, COPD, kidney problems, or other medical conditions that cause swelling. Make sure your prescriber knows about all of your medical conditions before you start Itraconazole (Sporanox) oral solution. Get medical help if you develop heart failure symptoms such as trouble breathing, feeling more tired than usual, swelling in your arms or legs, sudden weight gain, or a fast heart rate.

                        risk-warning

                        Abnormal heart rhythm

                        • Risk factors: Taking other medications that cause heart rhythm problems

                          Life-threatening heart rhythm problems have happened in people taking Itraconazole (Sporanox) oral solution together with medications like cisapride, pimozide, methadone, or quinidine. If you feel your chest pounding, have trouble breathing, have chest pain, or feel faint or lightheaded while taking Itraconazole (Sporanox) oral solution, call 911 right away.

                          risk-warning

                          Interactions with other medications

                          Itraconazole (Sporanox) oral solution is known to interact with many medications, including certain vitamins and herbal products. Some of these interactions can be dangerous or life-threatening.

                          Taking Itraconazole (Sporanox) oral solution with other medications can cause too much of either Itraconazole (Sporanox) oral solution or the other medication to build up in your body, which can raise your risk for serious side effects. On the other hand, Itraconazole (Sporanox) oral solution can also reduce the absorption of other medications, making them work less well.

                          Be sure to tell both your prescriber and pharmacist about all medications and over-the-counter (OTC) products you're taking before you start Itraconazole (Sporanox) oral solution, even if you only take them once in a while or as needed.

                          risk-warning

                          Liver damage

                          • Risk factors: History of liver problems | History of developing liver problems from other medications | Abnormal liver blood test results

                            Rarely, Itraconazole (Sporanox) oral solution can cause serious liver problems, including in the first week of treatment. Your prescriber might check your liver labs while you’re taking this medication. Stop taking Itraconazole (Sporanox) oral solution if you notice signs of liver problems, such as yellowing of the skin or eyes, dark urine, pale stools, or unusual tiredness.

                            risk-warning

                            Hearing loss

                            • Risk factors: Also taking quinidine | Older adults

                              Itraconazole (Sporanox) oral solution can cause hearing loss in some people. It usually gets better after you stop taking the medication, but for some people it can be permanent. Contact your prescriber right away if you notice trouble hearing after starting the medication. Let your care team know if you're taking quinidine because it shouldn't be taken with Itraconazole (Sporanox) oral solution due to a higher risk of hearing loss.

                              risk-warning

                              Nerve damage

                              If you have nerve problems like tingling sensations, reduced feeling, tremors, or other signs of nerve damage while taking Itraconazole (Sporanox) oral solution, stop taking the medication and call your prescriber.

                              dosage

                              Itraconazole (Sporanox) oral solution dosage forms

                              The average cost for 1 bottle of 150ml of 10mg/ml of Itraconazole (Sporanox) oral solution is $100.32 with a free GoodRx coupon. This is 63.17% off the average retail price of $272.38.
                              bottle of oral solution
                              Bottle of oral solution
                              DosageQuantityPrice as low asPrice per unit
                              150ml of 10mg/ml1 bottle$100.32$100.32

                              Typical dosing for Itraconazole (Sporanox) oral solution

                              • Oral thrush: The typical dose is 200 mg (20 mL) by mouth once a day on an empty stomach for 1 to 2 weeks.

                              • Oral thrush that didn’t get better with fluconazole: The typical dose is 100 mg (10 mL) by mouth twice a day on an empty stomach for 2 to 4 weeks.

                              • Fungal infections in the esophagus: The typical dose is 100mg (10 mL) by mouth once a day on an empty stomach for at least 3 weeks. Treatment should continue for 2 weeks after symptoms go away. Your prescriber might raise the dose to 200 mg (20 mL) once a day based on how well the medication is working for you.

                              interactions

                              Interactions between Itraconazole (Sporanox) oral solution and other drugs

                              Itraconazole (Sporanox) oral solution may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Itraconazole (Sporanox) oral solution. Please note that only the generic name of each medication is listed below.

                              Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

                              Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                              Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                              drug-cost

                              How much does Itraconazole (Sporanox) oral solution cost?

                              To access savings, use a GoodRx coupon and pay just a fraction of the retail price.View prices & coupons
                              contraindications-icon

                              Itraconazole (Sporanox) oral solution contraindications

                              Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Itraconazole (Sporanox) oral solution will not be safe for you to take.
                              alternatives

                              What are alternatives to Itraconazole (Sporanox) oral solution?

                              There are a number of medications that your doctor can prescribe in place of Itraconazole (Sporanox) oral solution. Compare a few possible alternatives below.
                              Itraconazole (Sporanox) oral solution
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                              latest news

                              What is the latest news about Itraconazole (Sporanox) oral solution?

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                              Itraconazole Coupon - Itraconazole 150ml of 10mg / ml bottle of oral solution
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                              References

                              Best studies we found

                              Drugs and Lactation Database (LactMed®). (2022). Itraconazole. National Institute of Child Health and Human Development.

                              Janssen Pharmaceuticals, Inc. (2024). Sporanox- itraconazole solution [package insert]. DailyMed.

                              Pappas, P. G., et al. (2015). Clinical Practice Guideline for the management of candidiasis: 2016 Update by IDSA. Clinical Infectious Diseases.

                              View All References (2)

                              Patel, M. A., et al. (2021). Common antifungal drugs in pregnancy: Risks and precautions. Journal of Obstetrics and Gynaecology of India.

                              U.S. Food and Drug Administration. (2023). Drug development and drug interactions | Table of substrates, inhibitors and inducers.

                              GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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