Type your drug name (like Atorvastatin, Sildenafil, etc)
Sirolimus Coupon - Sirolimus 1mg tablet
SirolimusGeneric Rapamune
SIROLIMUS is used to decrease the immune system's response to a transplanted organ. It is also used to treat a rare lung disease called lymphangioleiomyomatosis. The lowest GoodRx price for the most common version of sirolimus is around $136.62, 73% off the average retail price of $510.90. Compare mTOR inhibitors.
Prescription Settings
30 tablets
Sirolimus Coupon - Sirolimus 1mg tablet
30 tablets

Sirolimus Side Effects

What should I watch for?

Visit your doctor for regular checks on your progress. You will need frequent blood checks.

This medicine can cause your cholesterol or lipid levels to go up. You may need treatment for high cholesterol.

If you get a cold or other infection while receiving this medicine, call your doctor or health care professional. Do not treat yourself. The medicine may decrease your body's ability to fight infections.

This medicine may increase your risk of getting some cancers. Talk with your doctor.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.

Women who are able to have children should use effective birth control before, during, and for 12 weeks after stopping this medicine.


Common and Rare Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Abdominal or stomach cramps or pain

accumulation of pus

anxiousness, unexplained


black or red, tarry stools

bleeding from the gums or nose

blurred vision

body aches or pain

bone pain


burning or stinging of the skin

burning while urinating

burning, dry, or itching eyes

burning, tingling, numbness, or pain in the hands, arms, feet, or legs

change in mental status

changes in skin color

chest pain



convulsions (seizures)


dark or bloody urine


decreased urine output

decreased vision

difficulty with breathing or swallowing

dilated neck veins

discharge from the eyes



dry mouth


excessive tearing

extreme fatigue

eye pain

facial hair growth in females

faintness or lightheadedness when getting up from lying or sitting position

fast, slow, or irregular heartbeat


flushing or redness of the skin, especially on the face and neck

general feeling of discomfort or illness

increased hunger

increased menstrual flow or vaginal bleeding

itching, pain, redness, swelling, tenderness, or warmth on the skin

lack or loss of appetite

large, flat, blue, or purplish patches in the skin

loss of sexual ability, desire, drive, or performance

loss of voice

muscle pain

nasal congestion

nausea or vomiting

numbness or tingling around the lips, hands, or feet

pain in the chest, groin, or legs, especially the calves

painful cold sores or blisters on the lips, nose, eyes, or genitals

pale skin

prolonged bleeding from cuts

rapid heartbeat


red or dark brown urine

redness or swelling in the ear

redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid

ringing in the ears

runny nose

sensation of pins and needles

severe constipation

severe vomiting

severe, sudden headache

slurred speech

sore throat

sores or white spots on the lips or in the mouth

stomach pain or upset

sudden decrease in the amount of urine

sudden loss of coordination

sudden, severe weakness or numbness in the arm or leg

sudden, unexplained shortness of breath


swollen, painful, or tender lymph glands in the neck, armpit, or groin

tenderness, pain, swelling, warmth, skin discoloration, and prominent superficial veins over affected area


ulcers on the lips or in the mouth

unusual tiredness or weakness

vision changes

weakness or heaviness of the legs

white patches in the mouth or on the tongue

yellow skin and eyes

Less common


change in size, shape, or color of existing mole


mole that leaks fluid or bleeds

new mole

pains in the stomach, side or abdomen, possibly radiating to the back

skin ulcer or sores

Incidence not known

Abnormal wound healing


hives or itching

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

nails loose or detached

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

swelling of the arms or legs

yellow nails lacking a cuticle

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Abnormal vision



blistering, crusting, irritation, itching, or reddening of the skin

burning feeling in the chest or stomach

burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feeling


continuing ringing or buzzing or other unexplained noise in the ears

cracked, dry, or scaly skin


decrease in frequency of urination

degenerative disease of the joint



difficulty with moving

difficulty with passing urine (dribbling)


ear pain

enlarged abdomen or stomach


excess air or gas in the stomach or intestines

excessive muscle tone, muscle tension or tightness


feeling sad or empty

hearing loss


inability to have or keep an erection

increase in heart rate

increased hair growth, especially on the face

increased urge to urinate during the night


irritation in the mouth

joint pain or swelling

leg cramps

loss of bladder control

loss of energy or weakness

loss of interest or pleasure

loss of strength

lower abdominal or stomach pain

muscle aches, pain, stiffness, or weakness


pain in the back, ribs, arms, or legs

pain or burning in the throat

pain or tenderness around the eyes and cheekbones


pelvic pain

quick to react or overreact emotionally

rapid breathing

rapidly changing moods

inflammation, redness, or swelling of the gums or mouth

shaking or trembling



sunken eyes


swelling of the scrotum

tender or enlarged gums

tenderness in the stomach area

thickening of the skin

trouble concentrating

trouble sleeping

waking to urinate at night

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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