What should I watch for?
Visit your doctor or health care professional for regular checks on your progress. It may be several weeks before you see the full effects of this medicine.
Your health care provider may suggest that you have your eyes examined prior to starting this medicine, and every 6 months thereafter.
If you have been taking this medicine regularly for some time, do not suddenly stop taking it. You must gradually reduce the dose or your symptoms may get worse. Ask your doctor or health care professional for advice.
Patients and their families should watch out for depression or thoughts of suicide that get worse. Also watch out for sudden or severe changes in feelings such as feeling anxious, agitated, panicky, irritable, hostile, aggressive, impulsive, severely restless, overly excited and hyperactive, or not being able to sleep. If this happens, especially at the beginning of antidepressant treatment or after a change in dose, call your health care professional.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
This medicine can reduce the response of your body to heat or cold. Dress warm in cold weather and stay hydrated in hot weather. If possible, avoid extreme temperatures like saunas, hot tubs, very hot or cold showers, or activities that can cause dehydration such as vigorous exercise.
Side Effects to watch for
Side effects that you should report to your doctor or health care professional as soon as possible:
- allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
- difficulty swallowing
- fast or irregular heartbeat
- fever or chills, sore throat
- fever with rash, swollen lymph nodes, or swelling of the face
- increased hunger or thirst
- increased urination
- problems with balance, talking, walking
- stiff muscles
- suicidal thoughts or other mood changes
- uncontrollable head, mouth, neck, arm, or leg movements
- unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
What may interact with this drug?
Do not take this medicine with any of the following medications:
- certain medicines for fungal infections like fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole
- phenothiazines like chlorpromazine, mesoridazine, thioridazine
This medicine may also interact with the following medications:
- antiviral medicines for HIV or AIDS
- certain medicines for blood pressure
- certain medicines for depression, anxiety, or psychotic disturbances like haloperidol, lorazepam
- certain medicines for diabetes
- certain medicines for Parkinson's disease
- certain medicines for seizures like carbamazepine, phenobarbital, phenytoin
- other medicines that prolong the QT interval (cause an abnormal heart rhythm)
- steroid medicines like prednisone or cortisone