What should I watch for?
Report any side effects that you notice during your treatment right away, such as changes in your breathing, fever, chills, dizziness or lightheadedness. These effects are more common with the first dose.
Visit your prescriber or health care professional for checks on your progress. You will need to have regular blood work. Report any other side effects. The side effects of this medicine can continue after you finish your treatment. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.
Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This drug decreases your body's ability to fight infections. Try to avoid being around people who are sick.
This medicine may increase your risk to bruise or bleed. Call your doctor or health care professional if you notice any unusual bleeding.
Be careful brushing and flossing your teeth or using a toothpick because you may get an infection or bleed more easily. If you have any dental work done, tell your dentist you are receiving this medicine.
Do not become pregnant while taking this medicine. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine.
Common and Rare Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
Abdominal or stomach pain
black, tarry stools
bloating or swelling of the face, arms, hands, lower legs, or feet
blood in the urine or stools
body aches or pain
cough or hoarseness
difficulty with breathing
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
fever and chills
flushed, dry skin
fruit-like breath odor
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
lower back or side pain
pain or tenderness around the eyes and cheekbones
painful or difficult urination
pinpoint red spots on the skin
pounding in the ears
slow or fast heartbeat
sores, ulcers, or white spots in the mouth or on the lips
stuffy or runny nose
swelling of the tongue or throat
tightness of the chest
tingling of the hands or feet
troubled breathing with exertion
unusual bleeding or bruising
unusual tiredness or weakness
unusual weight gain or loss
Blistering, peeling, or loosening of the skin
blisters in the mouth
blisters on the trunk, scalp, or other areas
burning, crawling, itching, numbness, prickling, “pins and needles”, or tingling feeling
burning, tingling, numbness or pain in the hands, arms, feet, or legs
decreased frequency and amount of urination
difficulty with moving
feeling sad or empty
joint or muscle pain
loss of appetite
loss of interest or pleasure
muscle pain or stiffness
numbness or tingling in the hands, feet, or lips
pain at the injection site
pain, swelling, or redness in the joints
red skin lesions, often with a purple center
red, itchy lining of the eye
redness of the face, neck, arms, and occasionally, upper chest
Incidence not known
Abdominal or stomach cramps
blue-yellow color blindness
blurred vision or other change in vision
burning or stinging of the skin
dilated neck veins
eye pain, tearing
feeling of discomfort, illness, or weakness
painful cold sores or blisters on the lips, nose, eyes, or genitals
sensitivity of the eye to light
severe abdominal or stomach pain
severe vomiting, sometimes with blood
sores, welting, or blisters
swelling, stiffness, redness, or warmth around many joints
swollen and inflamed joints
swollen lymph glands
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
lack or loss of strength
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.