Ribociclib Side Effects
What should I watch for?
Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.
Do not take this medicine close to bedtime. It may prevent you from sleeping.
You may need blood work done while you are taking this medicine.
Do not become pregnant while taking this medicine or for 3 weeks after the last dose. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Men should inform their doctors if they wish to father a child. This medicine may lower sperm counts. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine or for 3 weeks after the last dose.
Be careful brushing and flossing your teeth or using a toothpick because you may get an infection or bleed more easily. If you have any dental work done, tell your dentist you are receiving this medicine.
Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This drug decreases your body's ability to fight infections. Try to avoid being around people who are sick.
This medicine may increase your risk to bruise or bleed. Call your doctor or health care professional if you notice any unusual bleeding.
Side Effects to watch for
Side effects that you should report to your doctor or health care professional as soon as possible:
- allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
- signs of decreased platelets or bleeding - bruising, pinpoint red spots on the skin, black, tarry stools, blood in the urine
- signs of decreased red blood cells - unusually weak or tired, feeling faint or lightheaded, falls
- signs of infection - fever or chills, cough, sore throat, pain or difficulty passing urine
- signs and symptoms of a dangerous change in heartbeat or heart rhythm like chest pain; dizziness; fast or irregular heartbeat; palpitations; feeling faint or lightheaded, falls; breathing problems
- signs and symptoms of liver injury like dark yellow or brown urine; general ill feeling or flu-like symptoms; light-colored stools; loss of appetite; nausea; right upper belly pain; unusually weak or tired; yellowing of the eyes or skin
- signs of low calcium like fast heartbeat, muscle cramps or muscle pain; pain, tingling, numbness in the hands or feet; seizures
- signs and symptoms of low magnesium like muscle cramps, pain, or weakness; tremors; seizures; or fast, irregular heartbeat
- signs and symptoms of low potassium like muscle cramps or muscle pain; chest pain; dizziness; feeling faint or lightheaded, falls; palpitations; breathing problems; or fast, irregular heartbeat
Side effects that usually do not require medical attention (report these to your doctor or health care professional if they continue or are bothersome):
What may interact with this drug?
Do not take this medicine with any of the following medications:
This medicine may interact with the following medications:
- antiviral medicines for HIV or AIDS
- certain medicines for fungal infections like ketoconazole, itraconazole, posaconazole, and voriconazole
- certain medicines for seizures like carbamazepine, phenobarbital, phenytoin
- ergot alkaloids like dihydroergotamine, ergonovine, ergotamine, methylergonovine
- grapefruit juice
- other medicines that prolong the QT interval (cause an abnormal heart rhythm)
- St. John's Wort