What should I watch for?
This medicine does not prevent heart attack or stroke. In fact, this medicine may increase the chance of a heart attack or stroke. The chance may increase with longer use of this medicine and in people who have heart disease. If you take aspirin to prevent heart attack or stroke, talk with your doctor or health care professional.
Do not take medicines such as ibuprofen and naproxen with this medicine. Side effects such as stomach upset, nausea, or ulcers may be more likely to occur. Many medicines available without a prescription should not be taken with this medicine.
This medicine can cause ulcers and bleeding in the stomach and intestines at any time during treatment. Do not smoke cigarettes or drink alcohol. These increase irritation to your stomach and can make it more susceptible to damage from this medicine. Ulcers and bleeding can happen without warning symptoms and can cause death.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.
This medicine can cause you to bleed more easily. Try to avoid damage to your teeth and gums when you brush or floss your teeth.
Common and Rare Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Burning feeling in chest or stomach
swelling or inflammation of the mouth
tenderness in stomach area
blistering, peeling, loosening of skin
bloody or black, tarry stools
bloody or cloudy urine
burning upper abdominal pain
changes in vision
difficult or labored breathing
fluid-filled skin blisters
general feeling of tiredness or weakness
greatly decreased frequency of urination or amount of urine
hives or welts
increased sensitivity of skin to sunlight
joint pain, stiffness, or swelling
large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, sex organs
loss of appetite
pain in lower back or side
pinpoint red spots on skin
puffiness or swelling of the eyelids or around the eyes, face, lips or tongue
red irritated eyes
red skin lesions, often with a purple center
redness or other discoloration of skin
severe or continuing stomach pain
shortness of breath
sores, ulcers, or white spots in mouth or on lips
stomach bloating, burning, or cramping
swelling of face, fingers, feet or lower legs
tightness in chest
unpleasant breath odor
unusual bleeding or bruising
unusual tiredness or weakness
vomiting of blood or material that looks like coffee grounds
weight gain or loss
yellow eyes or skin
Symptoms of overdose
irregular, fast or slow, or shallow breathing
pain or discomfort in chest, upper stomach, or throat
pale or blue lips, fingernails, or skin
pounding in the ears
severe stomach pain
unusual drowsiness, dullness, or feeling of sluggishness
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Acid or sour stomach
bloated full feeling
continuing ringing or buzzing or other unexplained noise in ears
excess air or gas in stomach or intestines
sleepiness or unusual drowsiness
unable to sleep
burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
feeling of constant movement of self or surroundings
general feeling of discomfort or illness
lack or loss of strength
sensation of spinning
shakiness in legs, arms, hands, feet
trembling or shaking of hands or feet
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.