Regorafenib Side Effects
What should I watch for?
This drug may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.
You may need blood work done while you are taking this medicine.
Do not become pregnant while taking this medicine or for 2 months after stopping it. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. Men should not father a child while taking this medicine and for 2 months after stopping it. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine.
If you are going to have surgery or any other procedures, tell your doctor you are taking this medicine.
Talk to your doctor about your risk of cancer. You may be more at risk for certain types of cancers if you take this medicine.
Common and Rare Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
bloody or cloudy urine
cough or hoarseness
coughing up blood
difficult, burning, or painful urination
difficulty with breathing or swallowing
fever or chills
frequent urge to urinate
increased menstrual flow or vaginal bleeding
lower back or side pain
painful or difficult urination
pounding in the ears
prolonged bleeding from cuts
red or black, tarry stools
redness, swelling, or pain of the skin
scaling of the skin on the hands and feet
slow or fast heartbeats
tingling of the hands and feet
ulcers on the skin
Chest pain or discomfort
general feeling of tiredness or weakness
nausea or vomiting
pain or discomfort in the arms, jaw, back, or neck
shakiness in the legs, arms, hands, or feet
stomach pain that continues
yellow eyes or skin
Blistering, peeling, or loosening of the skin
bloody, black, or tarry stools
joint or muscle pain
red skin lesions, often with a purple center
severe stomach pain, cramping, or burning
sores, ulcers, or white spots in the mouth or on the lips
unusual tiredness or weakness
vomiting of material that looks like coffee grounds, severe and continuing
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Bad, unusual, or unpleasant taste
hair loss or thinning of the hair
lack or loss of strength
muscle or joint stiffness
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.