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Ranibizumab
Lucentis (ranibizumab) is used to treat macular degeneration. Lucentis is also available as a biosimilar. Biosimilars are biologic drugs that are similar to the original medication with no meaningful differences in effectiveness or safety. The currently approved biosimliars for Lucentis are cimerli (ranibizumab-eqrn) and byooviz (ranibizumab-nuna). Lucentis may be covered by your Medicare or insurance plan. Compare VEGF antibodies.
Prescription Settings
Biologic Drug: Biologic drugs are made from living cells and are often expensive. Because biologic drugs are difficult to copy, they typically don’t have generic alternatives available. Learn More.

Ranibizumab Side Effects

What should I watch for?

Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse.

This medication can be given via an implanted device. Tell your care team if you have an implant and need an MRI. They will need to follow certain conditions to ensure you are safely scanned.

Side Effects (Rare and Common)

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

Blindness

bloody eye

blurred vision or loss of vision

decreased vision or other changes in vision

disturbed color perception

dizziness

double vision

dry eye

eye pain

fainting

feeling of having something in the eye

halos around lights

headache

night blindness

overbright appearance of lights

pain or tenderness around the eyes and cheekbones

red, sore eyes

redness of the white part of the eyes or inside of the eyelids

redness, swelling, or itching of the eyelid

seeing flashes or sparks of light

seeing floating spots before the eyes, or a veil or curtain appearing across a part of vision

sensitivity of the eye to light

tearing of the eyes

tunnel vision

watering of the eyes

Less common

Body aches or pain

chest pain

chills

cough

difficulty with breathing

dry mouth

fainting

fast, slow, or irregular heartbeat

general feeling of discomfort or illness

head congestion

hoarseness, loss of voice, or other voice changes

loss of consciousness

muscle aches and pains

nasal congestion

pain in the chest, groin, or legs, especially the calves

painful blisters on the trunk of the body

pale skin

runny nose

severe, sudden headache

shivering

slow wound healing

slurred speech

sneezing

sore throat

sudden loss of coordination

sudden, severe weakness or numbness in the arm or leg

sudden, unexplained shortness of breath

sweating

tightness in the chest

trouble sleeping

unexplained weight loss

unusual tiredness or weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Back pain

difficulty having a bowel movement (stool)

difficulty with moving

muscle stiffness

swelling or redness in the joints

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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