Availability: Qsymia is only available at select pharmacies and through the Qsymia Home Delivery program. Learn More
Insurance Coverage: Many major insurance plans no longer cover Qsymia. Learn More
Phentermine and Topiramate
Visit your doctor or health care professional for regular checks on your progress. This medicine is intended to be used in addition to a healthy diet and appropriate exercise. The best results are achieved this way. Do not increase or in any way change your dose without consulting your doctor or health care professional.
Do not take this medicine within 6 hours of bedtime. It can keep you from getting to sleep. Avoid drinks that contain caffeine and try to stick to a regular bedtime every night.
Do not stop taking this medicine suddenly. This increases the risk of seizures.
This medicine can decrease sweating and increase your body temperature. Watch for signs of deceased sweating or fever. Avoid extreme heat, hot baths, and saunas. Be careful about exercising, especially in hot weather. Contact your health care provider right away if you notice a fever or decrease in sweating.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may increase dizziness and drowsiness. Avoid alcoholic drinks.
This medicine may affect blood sugar levels. If you have diabetes, check with your doctor or health care professional before you change your diet or the dose of your diabetic medicine.
Patients and their families should watch out for worsening depression or thoughts of suicide. Also watch out for sudden changes in feelings such as feeling anxious, agitated, panicky, irritable, hostile, aggressive, impulsive, severely restless, overly excited and hyperactive, or not being able to sleep. If this happens, especially at the beginning of treatment or after a change in dose, call your health care professional.
If you notice blurred vision, eye pain, or other eye problems, seek medical attention at once for an eye exam.
This medicine may increase the chance of developing metabolic acidosis. If left untreated, this can cause kidney stones, bone disease, or slowed growth in children. Symptoms include breathing fast, fatigue, loss of appetite, irregular heartbeat, or loss of consciousness. Call your doctor immediately if you experience any of these side effects. Also, tell your doctor about any surgery you plan on having while taking this medicine since this may increase your risk for metabolic acidosis.
Women who become pregnant while using this medicine should contact their physician immediately. You should also contact The Qsymia Pregnancy Surveillance Program which is a program that monitors pregnancies that occur during treatment. Contact the program by calling 1-888-998-4887.
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
fast, irregular, pounding, or racing heartbeat or pulse
loss of appetite
muscle pain or cramps
nausea or vomiting
numbness or tingling in the hands, feet, or lips
shortness of breath
unusual tiredness or weakness
Incidence not known
Blistering, peeling, or loosening of the skin
blisters on the mouth, trunk, scalp, or other areas
blurred or decreased vision
chills or shivering
continuing nausea or vomiting
diarrhea or light-colored stools
increase in the frequency of seizures
joint or muscle pain
loss of appetite
low body temperature
muscle aches or weakness
pain in the shoulders, arms, jaw, or neck
red skin lesions, often with a purple center
red, irritated eyes
shakiness in the legs, arms, hands, or feet
sores, ulcers, or white spots in the mouth or on the lips
swelling of the face
tiredness and weakness
trouble thinking, speaking, or walking
upper right abdominal or stomach pain
weak or feeble pulse
yellow eyes or skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
change in taste
difficulty having a bowel movement (stool)
fear or nervousness
loss of taste
loss of voice
pain or tenderness around the eyes and cheekbones
stuffy or runny nose
heartburn or indigestion
stomach discomfort, upset, or pain
Incidence not known
false or unusual sense of well-being
feeling that others are watching you or controlling your behavior
feeling that others can hear your thoughts
feeling, seeing, or hearing things that are not there
hives or welts
change in sexual ability, desire, drive, or performance
severe mood or mental changes
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.