PROMETHAZINE prevents and treats the symptoms of an allergic reaction. It works by blocking histamine, a substance released by the body during an allergic reaction. It may also help you relax, go to sleep, and relieve nausea, vomiting, or pain before or after procedures. It can also prevent and treat motion sickness. It works by helping your nervous system calm down by blocking substances in the body that may cause nausea and vomiting. It belongs to a group of medications called antihistamines.

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