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Pertuzumab
Specialty Drug

Perjeta

PERTUZUMAB is a monoclonal antibody. It is used to treat breast cancer. Compare HER2 receptor antagonists.
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Pertuzumab Side Effects

What should I watch for?

Your condition will be monitored carefully while you are receiving this medicine. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.

Do not become pregnant while taking this medicine or for 7 months after stopping it. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. Women of child-bearing potential will need to have a negative pregnancy test before starting this medicine. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine or for 7 months after stopping it.

Women must use effective birth control with this medicine.

Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. Try to avoid being around people who are sick.

You may experience fever, chills, and headache during the infusion. Report any side effects during the infusion to your health care professional.

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Common and Rare Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

Black, tarry stools

burning, numbness, tingling, or painful sensations

chills

cough

fast heartbeat

fever

hives, itching, or rash

hoarseness

joint pain, stiffness, or swelling

lower back or side pain

painful or difficult urination

pale skin

redness of the skin

sore throat

swelling of the eyelids, face, lips, hands, or feet

tightness in the chest

troubled breathing or swallowing

ulcers, sores, or white spots in the mouth

unsteadiness or awkwardness

unusual bleeding or bruising

unusual tiredness or weakness

weakness in the arms, hands, legs, or feet

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Body aches or pain

change in taste

cracked lips

decreased appetite

diarrhea

dizziness

dry skin

ear congestion

hair loss or thinning of the hair

headache

loosening of the fingernails

loss of taste

loss of voice

nasal congestion

nausea

redness or soreness around the fingernails

runny nose

sneezing

vomiting

watering of the eyes

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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