Perampanel Side Effects
What should I watch for?
Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.
Visit your doctor or healthcare professional for regular checks on your progress. Wear a medical ID bracelet or chain, and carry a card that describes your disease and details of your medicine and dosage times.
It is important to take this medicine exactly as directed. When first starting treatment, your dose will need to be adjusted slowly. It may take weeks or months before your dose is stable. You should contact your doctor or healthcare professional if your seizures get worse or if you have any new types of seizures. Do not stop taking this medicine unless instructed by your doctor or healthcare professional. Stopping your medicine suddenly can increase your seizures or their severity.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
The use of this medicine may increase the chance of suicidal thoughts or actions. Pay special attention to how you are responding while on this medicine. Any worsening of mood, or thoughts of suicide or dying should be reported to your health care professional right away.
Common and Rare Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Aggression or anger
clumsiness or unsteadiness
deep or fast breathing with dizziness
numbness of the feet, hands, and around the mouth
sleepiness or unusual drowsiness
unsteadiness, trembling, or other problems with muscle control or coordination
unusual tiredness or weakness
Abnormal or decreased touch sensation
burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
Incidence not known
Changes in behavior
thoughts of killing oneself
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Dizziness or lightheadedness
feeling of constant movement of self or surroundings
sensation of spinning
bloating or swelling of the face, arms, hands, lower legs, or feet
body aches or pain
changes in speech patterns
decreased urine output
difficulty having a bowel movement
difficulty with moving
fast or irregular heartbeat
lack or loss of strength
loss of voice
muscle pain, cramps, or stiffness
pain in the arms, joints, or legs
trouble with speaking
unusual weight gain or loss
unusually deep sleep
Incidence not known
Unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.