Neratinib Side Effects
What should I watch for?
Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.
Do not become pregnant while taking this medicine or for 1 month after stopping it. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. Men should not father a child while taking this medicine and for 3 months after stopping it. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine or for 1 month after stopping it.
Check with your doctor or health care professional if you get an attack of severe diarrhea, nausea and vomiting, or if you sweat a lot. The loss of too much body fluid can make it dangerous for you to take this medicine.
You may need blood work done while you are taking this medicine.
Side Effects to watch for
Side effects that you should report to your doctor or health care professional as soon as possible:
- nausea, vomiting
- signs and symptoms of liver injury like dark yellow or brown urine; general ill feeling or flu-like symptoms; light-colored stools; loss of appetite; nausea; right upper belly pain; unusually weak or tired; yellowing of the eyes or skin
- signs and symptoms of low blood pressure like dizziness; feeling faint or lightheaded, falls; unusually weak or tired
- signs of infection - fever or chills, cough, sore throat, pain or difficulty passing urine
Side effects that usually do not require medical attention (report these to your doctor or health care professional if they continue or are bothersome):
What may interact with this drug?
This medicine may interact with the following medications:
- antiviral medicines for HIV or AIDS
- calcium channel blockers like diltiazem and verapamil
- certain antibiotics like clarithromycin, erythromycin and troleandomycin
- certain medicines for fungal infections like clotrimazole, fluconazole, ketoconazole, itraconazole, posaconazole, and voriconazole
- certain medicines for seizures like carbamazepine, phenobarbital, phenytoin
- grapefruit juice
- St. John's Wort
- stomach acid blockers like cimetidine, famotidine, lansoprazole, ranitidine, or omeprazole