FDA Update
Magnacet is part of the Opioid / Acetaminophen Combinations class and treats Pain. Opioid / acetaminophen combinations are used to treat pain and tension headaches. They work by reducing inflammation and by affecting parts of the brain to relieve pain. Magnacet is only available as a brand name drug. Compare opioid / acetaminophen combinations.

Magnacet Side Effects

Common and Rare Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Abdominal or stomach pain

black, tarry stools


dark urine





light-colored stools

loss of appetite



unpleasant breath odor

unusual tiredness or weakness

vomiting of blood

yellow eyes or skin


Cough or hoarseness

fever with or without chills

general feeling of tiredness or weakness

lower back or side pain

painful or difficult urination

sore throat

sores, ulcers, or white spots on the lips or in the mouth

unusual bleeding or bruising

Incidence not known

Back, leg, or stomach pains

bleeding gums


blood in the urine or stools

blue lips and fingernails

blurred vision

burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

chest pain or discomfort

clay-colored stools

cloudy urine




coughing that sometimes produces a pink frothy sputum

decreased awareness or responsiveness

decreased frequency or amount of urine

difficult or labored breathing

difficult or painful urination

difficult, fast, noisy breathing, sometimes with wheezing

difficulty in passing urine (dribbling)

difficulty with swallowing

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position


dry mouth

extremely shallow or slow breathing


fast or deep breathing

fast, slow, irregular, pounding, or racing heartbeat

feeling of warmth

general body swelling

increased sweating

increased thirst


large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs


muscle aches

muscle tremors

muscle weakness


noisy breathing


numbness or tingling in the hands, feet, or lips

pains in the stomach, side, or abdomen, possibly radiating to the back

pale skin

pinpoint red spots on the skin

pounding in the ears

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

rapid, deep or shallow breathing

redness of the face, neck, arms, and occasionally, upper chest



severe constipation

severe sleepiness

severe vomiting

skin blisters

skin rash, hives, or welts


sore throat

stomach cramps

sunken eyes


swelling of the face, fingers, lower legs, or ankles


tightness in the chest



weakness or heaviness of the legs

weight gain

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Bluish lips or skin

change in consciousness

cold, clammy skin

extreme sleepiness

general feeling of discomfort or illness

loss of consciousness

low blood pressure or pulse

slow breathing


Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Relaxed and calm feeling

Incidence not known

Acid or sour stomach


bad, unusual or unpleasant (after) taste


change in taste

cold sweats

constricted, pinpoint, or small pupils (black part of the eye)

continuing ringing or buzzing or other unexplained noise in the ears

cool, pale skin



difficulty with moving

disturbed color perception

double vision

excess air or gas in the stomach or intestines

false or unusual sense of well-being

flushed, dry skin

fruit-like breath odor

full feeling

general feeling of discomfort or illness

halos around lights

hearing loss


increased hunger

increased urination


joint pain

lack or loss of strength

muscle cramps or spasms

muscle pain or stiffness

night blindness


overbright appearance of lights

seeing, hearing, or feeling things that are not there



sleepiness or unusual drowsiness

slurred speech

stomach discomfort, upset, or pain


swollen joints


trouble sleeping

tunnel vision

unexplained weight loss

unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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