What is Komzifti?
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What should I tell my doctor?
They need to know if you have any of these conditions:
- Heart or blood vessel conditions
- Irregular heartbeat or rhythm
- Low levels of calcium, potassium, or magnesium in your blood
- Slow heartbeat
- An unusual or allergic reaction to ziftomenib, other medications, foods, dyes, or preservatives
- If you or your partner are pregnant or trying to get pregnant
- Breastfeeding
How should I use this drug?
Take this medication by mouth with water. Take it as directed on the prescription label at the same time every day. Do not cut, crush, or chew this medication. Swallow the capsules whole. Take it on an empty stomach, at least 1 hour before or 2 hours after food. Your care team may change your dose or tell you to stop taking this medication if you get side effects. Do not change your dose or stop taking it unless your care team tells you to.
Take medications that reduce stomach acid at a different time of day than this medication. Take antacids at least 2 hours before or 2 hours after this medication. Take H2 blockers, such as famotidine or cimetidine, at least 10 hours before or 2 hours after this medication.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your care team about the use of this medication in children. Special care may be needed.
What if I miss a dose?
If you miss a dose, take it as soon as you can, unless it is more than 12 hours late. If it is more than 12 hours late, skip that dose. Take your next dose at the normal time. Do not take double or extra doses.
Where should I store this drug?
Keep out of the reach of children and pets.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Get rid of any unused medication after the expiration date.
To get rid of medications that are no longer needed or have expired:
- Take the medication to a take-back program. Check with your pharmacy or law enforcement to find a location.
- If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, empty the medication out of the container. Mix it with cat litter, dirt, or coffee grounds, or another unwanted substance. Seal the mixture in a bag or container. Put it in the trash.
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