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Ketamine is an anesthetic. It is used to produce sleep before and during surgery. Compare NMDA receptor antagonists.

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Ketamine Side Effects

What should I watch for?

Your condition will be monitored carefully while you are receiving this medicine.

You may get dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Avoid alcoholic drinks; they can make you more dizzy.

Side Effects to watch for

Side effects that you should report to your doctor or health care professional as soon as possible:

allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
breathing problems
changes in vision
fast heartbeat
hallucination, loss of contact with reality
signs and symptoms of low blood pressure like dizziness; feeling faint or lightheaded, falls; unusually weak or tired
uncontrollable head, mouth, neck, arm, or leg movements
unusually slow heartbeat

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

anxious
excessive saliva production
upset stomach

What may interact with this drug?

Do not take this medicine with any of the following medications:

MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
St. John's Wort

This medicine may also interact with the following medications:

alcohol
antihistamines for allergy, cough, and cold
certain medicines for blood pressure
certain medicines for depression, anxiety, or psychotic disturbances
general anesthetics
medicines that relax muscles for surgery
memantine
narcotic medicines for pain
phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
pregabalin
theophylline; aminophylline
thyroid hormones

Other Conditions

Anesthesia

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