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Ionsys is part of the Opioids class and treats Pain. Opioids are used to treat pain, opioid dependence, and diarrhea. They work by affecting areas of the brain that sense pain and by allowing more fluid to be absorbed in the small intestine. Ionsys is only available as a brand name drug. Compare opioids.
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Ionsys Side Effects

Common and Rare Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Decrease in the amount of urine or in the frequency of urination

seeing, hearing, or feeling things that are not there

Less common

Chest pain

difficulty with speaking

fainting

mood or mental changes

problems with walking

redness, swelling, itching, or bumps on the skin at the place of application

spitting blood

Incidence not known

Bloating or swelling of the face, hands, lower legs, or feet

fast or pounding heartbeat or pulse

rapid weight gain

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Cold, clammy skin

convulsions (seizures)

drowsiness that is so severe you are not able to answer when spoken to or, if asleep, cannot be awakened

pinpoint (small) pupils in the eyes

slow heartbeat

very slow or troubled breathing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Abdominal or stomach pain that was not present before treatment

confusion

constipation

diarrhea

dizziness, drowsiness, or lightheadedness

false sense of well-being

feeling anxious

headache

indigestion

loss of appetite

nausea or vomiting

sweating

weakness

Less common

Feeling anxious and restless at the same time

feeling of crawling, tingling, or burning of the skin

memory loss

unusual dreams

Incidence not known

Change or problem with discharge of semen

decreased interest in sexual intercourse

inability to have or keep an erection

loss in sexual ability, desire, drive, or performance

not able to have an orgasm

weight loss

After you stop using this medicine, it may still produce some side effects that need attention. During this period of time, check with your doctor immediately if you notice the following side effects:

Body aches

fast heartbeat

fever, runny nose, or sneezing

gooseflesh feeling

increased sweating

increased yawning

nervousness, restlessness, or irritability

shivering or trembling

stomach cramps

trouble sleeping

unusually large pupils in the eyes

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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