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Gomekli
MIRDAMETINIB treats neurofibromatosis, a condition that causes tumors to grow along the nerves. It works by blocking a protein that causes tumor cells to grow and multiply. Compare kinase inhibitors.
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Gomekli Side Effects

What should I watch for?

Visit your care team for regular checks on your progress. Report any side effects. Continue your course of treatment even if you have side effects unless your care team tells you to stop.

You may need a test to check your heart before and during treatment. Talk to your care team right away if you have coughing, shortness of breath, swelling of the ankles, feet, or hands, fatigue, or an increased heart rate.

Your vision may be tested before and during use of this medication. Tell your care team right away if you have any change in your eyesight.

This medication can cause skin rashes. These rashes can be severe. Talk to your care team right away if you notice any type of skin problem while taking this medication. This includes itchy, red or dark patches of skin, raised bumps on the skin, skin bumps that look like acne, and peeling skin. Your care team can help you manage these side effects.

Talk to your care team if you or your partner may be pregnant. Serious birth defects can occur if you take this medication during pregnancy and for 6 weeks after the last dose. You will need a negative pregnancy test before starting this medication. Contraception is recommended while taking this medication and for 6 weeks after the last dose. Your care team can help you find the option that works for you.

If your partner can get pregnant, use a condom during sex while taking this medication and for 3 months after the last dose.

Do not breastfeed while taking this medication and for 1 week after the last dose.

This medication may cause infertility. Talk to your care team if you are concerned about your fertility.

What are the side effects?

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Blurry vision, vision loss, seeing wavy or bent objects or blind spots with dark, light, or flashing spots
  • Heart failure—shortness of breath, swelling of the ankles, feet, or hands, sudden weight gain, unusual weakness or fatigue
  • Redness, swelling, and blistering of the skin over hands and feet

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

What may interact with this drug?

Interactions have not been studied.

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