Futibatinib Side Effects
What should I watch for?
Visit your care team for regular check on your progress. It may be some time before you see the benefit from this medication.
You may need bloodwork while taking this medication.
This medication may cause dry eyes. If you wear contact lenses, you may feel some discomfort. Lubricating eye drops may help. See your care team if the problem does not go away or is severe.
Your vision may be tested before and during use of this medication. Tell your care team right away if you have any change in your eyesight.
Do not become pregnant while taking this medication or for 1 week after stopping it. Talk to your care team if you or your partner wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Contraception is recommended while taking this medication and for 1 week after stopping it. Talk to your care team about effective forms of contraception.
Do not breast-feed while taking this medication or for 1 week after stopping it.
What are the side effects?
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Blurry vision, vision loss, seeing wavy or bent objects or blind spots with dark, light, or flashing spots
- High phosphorus level—muscle pain or cramps, bone or joint pain, numbness and tingling around the mouth
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
- Bone, joint, or muscle pain
- Change in nail shape, thickness, or color
- Constipation
- Diarrhea
- Dry mouth
- Fatigue
- Nail lifting where the nail detaches from the nail bed
What may interact with this drug?
- Certain antibiotics, such as clarithromycin, rifampin, telithromycin
- Certain antiviral medications for HIV
- Certain medications for cancer, such as apalutamide, tucatinib
- Certain medications for fungal infections, such as ketoconazole, itraconazole, posaconazole
- Certain medications for seizures, such as carbamazepine, phenobarbital, phenytoin, primidone
- Grapefruit
- Lonafarnib
- Lumacaftor; ivacaftor
- St. John's Wort