Fludarabine Side Effects
What should I watch for?
This drug may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.
Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This drug decreases your body's ability to fight infections. Try to avoid being around people who are sick.
This medicine may increase your risk to bruise or bleed. Call your doctor or health care professional if you notice any unusual bleeding.
Be careful brushing and flossing your teeth or using a toothpick because you may get an infection or bleed more easily. If you have any dental work done, tell your dentist you are receiving this medicine.
Do not become pregnant while taking this medicine. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine.
Men should inform their doctors if they wish to father a child. This medicine may lower sperm counts.
Common and Rare Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
Arm, back, or jaw pain
black, tarry stools
blood in the urine or stools
chest pain or discomfort
chest tightness or heaviness
cough or hoarseness
coughing or spitting up blood
fast or irregular heartbeat
fever or chills
general feeling of discomfort or illness
lower back or side pain
painful, burning, or difficult urination
pinpoint red spots on the skin
shortness of breath
sores, ulcers, or white spots on the lips or in the mouth
stomach pain, severe
tender, swollen glands in the neck
thickening of bronchial secretions
unusual bleeding or bruising
unusual tiredness or weakness
vomiting of blood or material that looks like coffee grounds
decreased urine output
difficulty in breathing or swallowing
dilated neck veins
fast, pounding, or irregular heartbeat or pulse
increased menstrual flow or vaginal bleeding
loss of hearing
numbness or tingling in the fingers, toes, or face
pain, redness, or swelling in the arm or leg
prolonged bleeding from cuts
sudden and severe inability to speak
weakness in the arm or leg on one side of the body, sudden and severe
loss of appetite
loss of consciousness
lower abdominal cramping
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
rapid, deep breathing
trouble speaking, thinking, or walking
yellow eyes or skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
body aches or pain
burning, crawling, itching, numbness, prickling, “pins and needles”, or tingling feelings
difficulty in moving
dry mouth or throat
flushed, dry skin
frequent urge to urinate
fruit-like breath odor
muscle aching or cramping
muscle pains or stiffness
trouble in swallowing
bluish color of skin
changes in skin color
decrease in height
difficulty in sleeping
feeling sad or empty
gaseous abdominal pain
loss of interest or pleasure
pain or tenderness around the eyes and cheekbones
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.