Just last week, the Food and Drug Administration (FDA) released a new warning for SGLT2 inhibitors, a class of drugs used to lower blood sugar in adults with type 2 diabetes. According to the FDA, a serious bacterial infection known as necrotizing fasciitis has been reported in the genital area of some patients taking SGLT2 inhibitors. While this condition is rare and only 12 cases have been confirmed since 2013, necrotizing fasciitis spreads rapidly and can be deadly. See More
Farxiga Latest News
Get the latest updates on this drug from the GoodRx medical team
After decades of little innovation in treatments for type 1 diabetes, the FDA is on track to approve Zynquista, the first oral antidiabetic drug in the US for adults with type 1 diabetes, by March 2019.
Current type 1 diabetes medications
At present, those with type 1 diabetes, also known as juvenile or insulin-dependent diabetes, use injectable or inhaled insulins to survive. Sometimes, they also use Symlin, an injectable non-insulin drug that makes patients feel full at meals, slows the rate at which food moves from the stomach into the small intestine, and stops the release of glucagon, a hormone that tells the liver to release sugar into the bloodstream. See More
Let’s start with the bad news. Invokana, a tablet taken to treat type 2 diabetes, is really expensive. A 30-day supply of Invokana can cost around $550, and we may have to wait another six years to see a generic. But there is good news — there are ways to save.
Here’s all the information you need to make your Invokana prescription affordable.
How popular is Invokana?
Approved in 2013, Invokana is one of the most popular SGLT2 inhibitors, a class of drugs that is used to treat diabetes type 2 by blocking the kidneys from reabsorbing glucose so any excess is excreted from the body. See More
This update is the result of new data from the CANVAS and CANVAS-R clinical trials. This research showed that leg and foot amputations occurred two times more often in patients treated with canagliflozin than in patients who were given a placebo sugar pill. See More
According to The American Diabetes Association, as of 2012, type 2 diabetes affected 29.1 million Americans, 9.3% of the population. Every year another 1.4 million Americans are diagnosed with type 2 diabetes, which can lead to live-threatening complications like high-blood pressure, kidney disease, high cholesterol, or loss of vision.
Recently, the FDA approved Qtern (dapagliflozin and saxagliptin), a new combination prescription medication for adults with type 2 diabetes. See More
According to the FDA, canagliflozin and dapagliflozin may cause an increased risk of acute kidney injury. The previous warning for canagliflozin was for an increased risk of foot and leg amputations—all serious stuff. See More
On May 15, 2015, the FDA issued a warning for the newest class of diabetes medications, SGLT2 inhibitors.
According to the FDA, the medications in this class may lead to a serious and life-threatening condition known as ketoacidosis.
Which medications are considered SGLT2 inhibitors?
These medications also contain SGLT2 inhibitors in combination with other active ingredients:
- Glyxambi (empagliflozin/linagliptin)
- Invokamet (canagliflozin/metformin)
- Xigduo XR (dapagliflozin/metformin)
What should I do if I am taking one of these medications?
If you are taking one of the medications listed above DO NOT stop your medication without talking to your doctor. See More
For many Americans with health insurance, more than 40 popular brand-name drugs may no longer be covered starting in January 2015. Express Scripts and Caremark, companies that handle pharmacy benefits for more than 200 million Americans, are removing over 40 drugs from their formularies at the end of 2014. This is in addition to the more than 50 drugs removed last year.
What are Express Scripts and Caremark?
Express Scripts and Caremark are companies that administer prescription drug benefits for many health insurance companies and Tricare. See More
Jardiance (empagliflozin) was approved by the FDA on August 1, 2014 for the treatment of type 2 diabetes.
How does Jardiance work?
It works with the body’s natural process of urination to help remove more excess sugar from the body rather than allowing it to be reabsorbed by your kidneys. See More
With 25 million Americans with adult-onset diabetes I guess it’s great we have so many new medications coming down the pipeline. As a primary care doctor, even my head is spinning learning the details of the newest diabetes medications but it’s exciting . . . and here is another one.