Prescription Prices and Coupons from GoodRx
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Isometheptene / Dichloralphenazone / Acetaminophen Coupon - Isometheptene / Dichloralphenazone / Acetaminophen 65mg/100mg/325mg capsule
Epidrine, Midrin
FDA Update
Isometheptene / Dichloralphenazone / Acetaminophen
ACETAMINOPHEN; DICHLORALPHENAZONE; ISOMETHEPTENE is a pain reliever. It is used to treat migraine or tension headaches. The lowest GoodRx price for the most common version of isometheptene / dichloralphenazone / acetaminophen is around $58.29, 64% off the average retail price of $165.95. Compare sympathomimetic / NSAID combinations.
Prescription Settings
isometheptene / dichloralphenazone / acetaminophen(generic)
30 capsules
Isometheptene / Dichloralphenazone / Acetaminophen Coupon - Isometheptene / Dichloralphenazone / Acetaminophen 65mg/100mg/325mg capsule
isometheptene / dichloralphenazone / acetaminophen(generic)
30 capsules

Epidrine Side Effects

What should I watch for?

Visit your doctor or health care provider for regular check ups. Tell your doctor if your pain does not go away, if it gets worse, or if you have new or a different type of pain. Do not share this medicine with anyone else.

This medicine contains acetaminophen. Many over the counter medicines also contain acetaminophen as an ingredient. To prevent overdose, read labels carefully. Do not take this medicine with other acetaminophen products.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

If you take migraine medicines for 10 or more days a month, your migraines may get worse. Keep a diary of headache days and medicine use. Contact your healthcare professional if your migraine attacks occur more frequently.


Common and Rare Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common or rare


difficulty in swallowing

dizziness, lightheadedness, or feeling faint (severe)

flushing, redness, or other change in skin color

shortness of breath, troubled breathing, tightness in chest, or wheezing

sudden decrease in amount of urine

swelling of eyelids, face, or lips

Get emergency help immediately if any of the following symptoms of overdose occur:

Signs and symptoms of overdose

Agitation, anxiety, excitement, irritability, nervousness, or restlessness

any loss of hearing

bloody urine

confusion or delirium

convulsions (seizures)

diarrhea (severe or continuing)

dizziness or lightheadedness

drowsiness (severe)

fast or deep breathing

fast or irregular heartbeat (for medicines containing caffeine

frequent urination (for medicines containing caffeine)

hallucinations (seeing, hearing, or feeling things that are not there)

increased sensitivity to touch or pain (for medicines containing caffeine)

increased sweating

loss of appetite

muscle trembling or twitching (for medicines containing caffeine)

nausea or vomiting (continuing, sometimes with blood)

ringing or buzzing in ears (continuing)

seeing flashes of lights (for medicines containing caffeine)

stomach cramps or pain (severe or continuing)

swelling, pain, or tenderness in the upper abdomen or stomach area

trouble in sleeping (for medicines containing caffeine)

uncontrollable flapping movements of the hands, especially in elderly patients

unexplained fever

unexplained fever

Signs of overdose in children

Changes in behavior

drowsiness or tiredness

fast or deep breathing

Check with your doctor as soon as possible if any of the following side effects occur:

Less common or rare

Bloody or black, tarry stools

bloody or cloudy urine

fever with or without chills (not present before treatment and not caused by the condition being treated)

pain in lower back and/or side (severe and/or sharp)

pinpoint red spots on skin

skin rash, hives, or itching

sores, ulcers, or white spots on lips or in mouth

sore throat (not present before treatment and not caused by the condition being treated)

stuffy nose

swelling of face, fingers, feet, or lower legs

unusual bleeding or bruising

unusual tiredness or weakness

vomiting of blood or material that looks like coffee grounds

weight gain

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Heartburn or indigestion (for medicines containing aspirin)

nausea, vomiting, or stomach pain (for medicines containing aspirin)

Less common

Drowsiness (for medicines containing salicylamide)

trouble in sleeping, nervousness, or jitters (for medicines containing caffeine)

After you stop using this medicine, it may still produce some side effects that need attention. During this period of time, check with your doctor immediately if you notice the following side effects:


Bloody or cloudy urine

decreased urination

swelling of face, fingers, feet, or lower legs

weight gain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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