What should I watch for?
Tell your doctor or health care professional if your symptoms do not start to get better or if they get worse. Your gout may get worse (flare up) when you first start this medicine. Do not stop taking this medicine even if you have a flare. Your doctor or health care professional may give you other medicines to help prevent your gout flares.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this drug affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can make you more drowsy and dizzy. Alcohol can also increase the chance of stomach problems and increase the amount of uric acid in your blood. Avoid alcoholic drinks.
You may need blood work done while you are taking this medicine.
Side Effects to watch for
Side effects that you should report to your doctor or health care professional as soon as possible:
- allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
- breathing problems
- fever with rash, swollen lymph nodes, or swelling of the face
- joint pain
- muscle pain
- redness, blistering, peeling or loosening of the skin, including inside the mouth
- signs and symptoms of a heart attack like breathing problems; chest pain or discomfort; feeling faint or lightheaded, falls; nausea, vomiting; back or jaw pain
- signs and symptoms of infection like fever or chills; cough; sore throat
- signs and symptoms of kidney injury like trouble passing urine or change in the amount of urine, flank pain
- signs and symptoms of a stroke like changes in vision; confusion; trouble speaking or understanding; severe headaches; sudden numbness or weakness of the face, arm, or leg; trouble walking; dizziness; loss of balance or coordination
- tingling, numbness in the hands or feet
- unusual bleeding or bruising
- unusually weak or tired
Side effects that usually do not require medical attention (report these to your doctor or health care professional if they continue or are bothersome):
What may interact with this drug?
Do not take this medicine with the following medication:
- didanosine, ddI
This medicine may also interact with the following medications:
- certain antibiotics like amoxicillin, ampicillin, and rifampin
- certain medicines for blood pressure, heart disease, irregular heart beat like amiodarone, amlodipine
- certain medicines for cancer
- certain medicines for cholesterol like atorvastatin
- certain medicines for fungal infections, like fluconazole
- certain medicines for immunosuppression like azathioprine, cyclosporine, mercaptopurine
- certain medicines for seizures like carbamazepine, valproic acid
- certain medicines that treat or prevent blood clots like warfarin
- female hormones, like estrogens and progestins and birth control pills, patches, rings, or injections
- thiazide diuretics, like hydrochlorothiazide