Deutetrabenazine Side Effects
What should I watch for?
Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
Patients and their families should watch out for worsening depression or thoughts of suicide. If this happens, especially at the beginning of treatment or after a change in dose, call your health care professional.
Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.
Tell your doctor or health care professional right away if you have any change in your eyesight.
Side Effects to watch for
Side effects that you should report to your doctor or health care professional as soon as possible:
- allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
- changes in vision
- feeling faint or lightheaded, falls
- loss of balance or coordination
- suicidal thoughts or other mood changes
- restlessness, pacing, inability to keep still
- signs and symptoms of a dangerous change in heartbeat or heart rhythm like chest pain; dizziness; fast or irregular heartbeat; palpitations; feeling faint or lightheaded, falls; breathing problems
- signs and symptoms of neuroleptic malignant syndrome (NMS) such as confusion; fast or irregular heart beat; high fever; increased sweating; uncontrolled head, mouth, neck, arm, or leg movements; stiff muscles
Side effects that usually do not require medical attention (report these to your doctor or health care professional if they continue or are bothersome):
What may interact with this drug?
Do not take this medicine with any of the following medications:
- MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
This medicine may also interact with the following medications:
- antihistamines for allergy, cough and cold
- certain medicines for depression, anxiety, or psychotic disturbances
- certain medicines for sleep
- certain medicines for seizures like phenobarbital, primidone
- general anesthetics like halothane, isoflurane, methoxyflurane, propofol
- local anesthetics like lidocaine, pramoxine, tetracaine
- medicines that relax muscles for surgery
- narcotic medicines for pain or cough
- other medicines that prolong the QT interval (cause an abnormal heart rhythm)
- phenothiazines like chlorpromazine, fluphenazine, perphenazine, prochlorperazine, trifluoperazine