What should I watch for?
Visit your doctor or health care professional for regular check ups. Discuss any new symptoms with your doctor. You will need to have important blood work done while on this medicine.
Birth control pills may not work properly while you are taking this medicine. Talk to your doctor about using an extra method of birth control. Women who can still have children must use a reliable form of barrier contraception, like a condom.
This medicine may affect blood sugar levels. If you have diabetes, check with your doctor or health care professional before you change your diet or the dose of your diabetic medicine.
Side Effects to watch for
Side effects that you should report to your doctor or health care professional as soon as possible:
- allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
- dark urine
- loss of appetite
- nausea, vomiting, abdominal pain
- pain in the lower back or side
- pain when urinating
- redness, blistering, peeling or loosening of the skin, including inside the mouth
- trouble passing urine or change in the amount of urine
- unusually weak or tired
- yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
What may interact with this drug?
Do not take this medicine with any of the following medications:
- certain medicines for blood pressure, heart disease, irregular heart beat like dronedarone, ranolazine
- certain medicines for seizures like carbamazepine, fosphenytoin, phenytoin, phenobarbital
- colchicine (if you have liver or kidney problems)
- elbasvir and grazoprevir
- medicines for cholesterol like lovastatin, simvastatin
- medicines for headaches like dihydroergotamine, ergotamine, methylergonovine
- sildenafil (for the treatment of pulmonary arterial hypertension)
- St. John's wort
This medicine may also interact with the following medications:
- artemether; lumefantrine
- certain antibiotics like clarithromycin, erythromycin, telithromycin, rifabutin, rifapentine
- certain other antiviral medicines for HIV or AIDS like atazanavir, didanosine, efavirenz, elvitegravir, etravirine, fosamprenavir, indinavir, lopinavir; ritonavir, maraviroc, nelfinavir, nevirapine, ritonavir, saquinavir, tenofovir, tipranavir
- certain medications for anxiety or sleep like buspirone, diazepam, estazolam, zolpidem
- certain medicines for blood pressure and heart disease like amlodipine, carvedilol, diltiazem, felodipine, metoprolol, nifedipine, timolol, verapamil
- certain medicines for cancer like dasatinib, nilotinib, vinblastine, vincristine
- certain medicines for depression like amitriptyline, desipramine, imipramine, nortriptyline, paroxetine, sertraline, and trazodone
- certain medicines for erectile dysfunction like avanafil, sildenafil, tadalafil, vardenafil
- certain medicines for fungal infection like itraconazole, ketoconazole, posaconazole, voriconazole
- certain medicines for hepatitis infection like boceprevir, simeprevir
- certain medicines for psychiatric disturbances like perphenazine, quetiapine, risperidone, thioridazine
- certain medicines for seizures like clonazepam, eslicarbazepine, oxcarbazepine
- certain medicines that treat or prevent blood clots like apixaban, dabigatran, rivaroxaban, warfarin
- female hormones, like estrogens and progestins and birth control pills
- medicines for cholesterol like atorvastatin, fluvastatin, pitavastatin, pravastatin, rosuvastatin
- medicines for irregular heart beat like amiodarone, digoxin, disopyramide, flecainide, lidocaine, mexiletine, propafenone, quinidine
- medicines that lower your chance of fighting infection like cyclosporine, everolimus, sirolimus, tacrolimus
- narcotic medicines for pain like buprenorphine, buprenorphine; naloxone, fentanyl, methadone, oxycodone, tramadol
- steroid medicines like betamethasone, budesonide, ciclesonide, dexamethasone, fluticasone, methylprednisolone, mometasone, prednisolone, triamcinolone
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also, tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.