Duavee (conjugated estrogens/bazedoxifene) is used to treat hot flashes and prevent osteoporosis. Duavee is slightly less popular than other estrogen agonist/antagonists. There are currently no generic alternaties to Duavee.
GoodRx has partnered with InsideRx and Pfizer to reduce the price for this prescription. Check our savings tips for co-pay cards, assistance programs, and other ways to reduce your cost. Duavee is covered by most Medicare and insurance plans.
Conjugated Estrogens and Bazedoxifene Side Effects
What should I watch for?
Do not take a progestin product or additional estrogen or estrogen-like products while taking this drug. Discuss the risks and benefits of taking this drug with your prescriber.
Visit your health care professional for regular checks on your progress. You will need a regular breast and pelvic exam and Pap smear while on this medicine. You should also discuss the need for regular mammograms with your health care professional, and follow his or her guidelines for these tests.
This medicine can make your body retain fluid, making your fingers, hands, or ankles swell. Your blood pressure can go up. Contact your doctor or health care professional if you feel you are retaining fluid.
You should make sure you get enough calcium and vitamin D in your diet while you are taking this medicine. Discuss your dietary needs with your health care professional or nutritionist.
Exercise may help to prevent bone loss. Discuss your exercise needs with your doctor or health care professional.
This medicine can rarely cause blood clots. You should avoid long periods of bed rest while taking this medicine. If you are going to have surgery, tell your doctor or health care professional that you are taking this medicine. This medicine should be stopped at least 3 days before surgery. After surgery, it should be restarted only after you are walking again. It should not be restarted while you still need long periods of bed rest.
Smoking increases the risk of getting a blood clot or having a stroke while you are taking this medicine, especially if you are more than 35 years old. You are strongly advised not to smoke.
If you have any reason to think you are pregnant; stop taking this medicine at once and contact your doctor or health care professional.
If you wear contact lenses and notice visual changes, or if the lenses begin to feel uncomfortable, consult your eye care specialist.
Common and Rare Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Incidence not known
Acid or sour stomach
change in vaginal discharge
clear or bloody discharge from the nipple
difficulty with speaking
dimpling of the breast skin
dizziness or lightheadedness
full or bloated feeling or pressure in the stomach
inability to move the arms, legs, or facial muscles
inability to speak
loss of appetite
lump in the breast or under the arm
pain or feeling of pressure in the pelvis
pain, redness, or swelling in the arm or leg
pains in the stomach, side, or abdomen, possibly radiating to the back
persistent crusting or scaling of the nipple
redness or swelling of the breast
sore on the skin of the breast that does not heal
stomach discomfort, upset, or pain
sudden shortness of breath or troubled breathing
swelling of the abdominal or stomach area
yellow eyes or skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.