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Keflex vs. Avelox

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Cephalexin (generic name: cephalexin) and Avelox (generic name: moxifloxacin) are both antibiotics, but they belong to different classes and treat infections differently. Cephalexin is a cephalosporin antibiotic that works by preventing bacteria from forming a protective covering, making it effective against a wide range of bacterial infections like UTIs, ear infections, and skin infections. It's typically taken 2 to 4 times a day and is available in generic forms like capsules, tablets, and liquid suspensions. On the other hand, Avelox is a fluoroquinolone antibiotic that kills bacteria by blocking enzymes they need to grow and repair their genetic material. It's usually prescribed for more serious infections or when other antibiotics aren't suitable, and it's availible as a generic that is taken once daily. Avelox can cause serious side effects like tendon rupture and nerve damage, making it less commonly used compared to cephalexin. While both medications can cause common side effects like nausea and diarrhea, Avelox has additional risks like heart rhythm problems and severe allergic reactions. Cephalexin is generally considered safe during pregnancy and breastfeeding, whereas the safety of Avelox in these conditions is not well-established.

Cephalexin

 

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Moxifloxacin

(Avelox)

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Summary for Keflex

Prescription only

Cephalexin, also commonly known as Keflex, is a cephalosporin antibiotic for people ages 1 year and older. It can treat many types of bacterial infections. This includes ear infections, skin infections like cellulitis, urinary tract infections (UTIs), and strep throat. Cephalexin comes as capsules, tablets, and a liquid suspension. It's taken by mouth 2 to 4 times per day. Side effects can include nausea, vomiting, and diarrhea. Cephalexin is a generic medication; its brand name Keflex is no longer available.

Indications for Keflex

Pros and Cons for Keflex

Pros

  • Treats several common types of bacterial infections
  • Okay for children as young as 1 year old to take
  • Available as a liquid for people who have trouble swallowing pills

Cons

  • Usually need to take a few times per day
  • Might not be able to take if you're allergic to penicillins or other cephalosporin antibiotics
  • Not recommended for the cold or flu (these are viral illnesses, not bacterial infections)

Common Side Effects for Keflex

  • Diarrhea
  • Nausea
  • Vomiting
  • Indigestion
  • Stomach pain

Warnings for Keflex

  • Allergic reactions
  • Diarrhea from Clostridioides difficile infection
  • Seizures
  • Higher risk of bleeding
  • Possible development of drug-resistant bacteria

Summary for Avelox

Prescription only

Moxifloxacin (Avelox) is a fluoroquinolone antibiotic. It can treat different types of infections, including certain skin infections and lung infections, in adults. But because moxifloxacin (Avelox) can cause serious side effects, such as tendon rupture and nerve damage, it's usually only prescribed for more serious infections or when safer options aren't available. Moxifloxacin (Avelox) is taken by mouth, typically once daily. Some of the more common side effects of this medication include nausea, diarrhea, and headache. Moxifloxacin is generic only, brand-name Avelox is no longer available.

Indications for Avelox

Treatment of certain bacterial infections, including:

Pros and Cons for Avelox

Pros

  • Can take with or without food
  • Only taken once a day
  • Treats many types of infections
  • Might be an option for people who have penicillin allergy

Cons

Common Side Effects for Avelox

  • Nausea (7%)
  • Diarrhea (6%)
  • Headache (4%)
  • Dizziness (3%)
  • Trouble sleeping (2%)
  • Vomiting (2%)
  • Constipation (2%)
  • Belly pain (2%)

Warnings for Avelox

  • Tendon inflammation and rupture
  • Effects on the brain, nerves, and mental health
  • Worsening of myasthenia gravis
  • Heart rhythm problems (QT prolongation)
  • Severe allergic and skin reactions
  • Severe damage to a major blood vessel
  • Severe infectious diarrhea
  • Changes in blood sugar
  • Sun and light sensitivity

Prices with our coupons for Keflex vs. Avelox

Price Card Drug Icon
Cephalexin28 capsules / 500mg
$10.68$29.97
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Moxifloxacin7 tablets / 400mg
$23.92$106.08
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