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Estradiol

Estradiol (Estrace, Vivelle-Dot, Climara) is a moderately priced drug used to treat hot flashes and osteoporosis. It is also used to treat women with low estrogen levels or those who have had their ovaries removed. This drug is more popular than comparable drugs. It is available in multiple generic and brand versions. It is covered by some Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost. The lowest GoodRx price for the most common version of estradiol is around $32.09, 59% off the average retail price of $79.38. Compare estrogens.

Looking for a compounded prescription? You can find prices and coupons here.

Climara Latest News

Get the latest updates on this drug from the GoodRx medical team

Here’s What Gayle Did When Her Mail Order Pharmacy Got Too Expensive

Katie Mui - May 17, 2018

Skipping the pharmacy line and getting your prescriptions mailed to you may seem like an easy choice, but as Gayle learned, mail order pharmacies don’t always offer the best price.

For years, Gayle had relied on a mail order pharmacy to fill her prescription for estradiol patches, simply because her insurer had offered it as a member benefit. She didn’t think — or rather didn’t know — that she was actually paying too much for her medications. See More

Here’s How to Save on Premarin For Menopause

Tori Marsh - March 16, 2018

If you’re over the age of 50, you may have started to experience some of those difficult menopause symptoms. Hot flashes, fatigue, night sweats, osteoporosis…not fun.

Luckily there are medications that can help you through menopause. But are they affordable?

One of the more commonly prescribed estrogens to treat menopausal symptoms and prevent osteoporosis is Premarin, but it’s expensive. Premarin is a brand-only medication, and a 30-day supply can cost well over $200. See More

Patch vs Pills for Estrogen Replacement

Dr. Sharon Orrange - September 12, 2017

Many women struggle with lack of interest in sex after menopause. Lower estrogen with menopause may result in vaginal dryness, painful intercourse and—because estrogen helps regulate the parts of the brain that control mood and desire—libido takes a hit as well. Many women come to primary care doctors for help when sexual desire is lacking and they want to get back to the days when they felt desire and satisfaction. See More

Why Is Premarin So Expensive?

Dr. Sharon Orrange - August 04, 2014

Many women need cheaper options for hormone replacement. One of the most commonly prescribed estrogens for women is Premarin, and it’s so darn expensive. This is because there is no generic form of Premarin and will not likely ever be. Premarin is the brand name for conjugated estrogens used to treat symptoms of menopause and to prevent osteoporosis.

Why doesn’t a generic for Premarin exist?

Well, because we don’t really know what’s in it. See More

Patch Over Pill

Dr. Sharon Orrange - September 07, 2012

Women have fallen in love with estrogen patches instead of pills for hormone replacement therapy, yet are continually stung by the cost. There is now a generic option for an estrogen patch that has become a game changer, so let’s get to know our options.

Estradiol is used to prevent osteoporosis and relieve symptoms associated with menopause. Estradiol is the principal intracellular human estrogen and is available in many dosage forms, including transdermal patches, topical creams, gels or sprays, vaginal creams, oral tablets, vaginal rings, and injections. See More

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