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HomeDrugsChlorhexidine
01:10

Chlorhexidine: How It Works, How to Take It, and Side Effects

Also known as Peridex, this mouthwash can help treat gingivitis.

Lauren Smith, MAChristina Aungst, PharmD
Written by Lauren Smith, MA | Reviewed by Christina Aungst, PharmD
Published on February 13, 2025

Chlorhexidine (Peridex) is an antiseptic mouthwash. It kills germs by destroying their protective coverings, which helps prevent plaque and treat gingivitis.

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Additional Medical Contributors
  • Joshua Murdock, PharmD, BCBBSJoshua Murdock, PharmD is a pharmacy editor for GoodRx. He earned his Doctor of Pharmacy degree from Butler University in Indianapolis, Indiana and is licensed in Colorado and Rhode Island.

    References

    Brookes, Z. L. S., et al. (2020). Current uses of chlorhexidine for management of oral disease: A narrative review. Journal of Dentistry.

    Chartwell RX, LLC. (2023). Chlorhexidine gluconate 0.12% oral rinse- chlorhexidine gluconate 0.12% oral rinse solution [package insert]. DailyMed.

    View All References (3)

    Frank, M. E., et al. (2001). Effects of chlorhexidine on human taste perception. Physiology & Behavior.

    Henry Schein, Inc. (2023). Acclean chlorhexidine gluconate 0.12% oral rinse- chlorhexidine gluconate solution [package insert]. DailyMed.

    Poppolo Deus, F., et al. (2022). Chlorhexidine in dentistry: Pharmacology, uses, and adverse effects. International Dental Journal.

    GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.

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