Carfilzomib Side Effects
What should I watch for?
Your condition will be monitored carefully while you are receiving this medicine. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.
You may need blood work done while you are taking this medicine.
Do not become pregnant while taking this medicine or for at least 6 months after stopping it. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Men should not father a child while taking this medicine and for at least 3 months after stopping it. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine or for 2 weeks after the last dose.
Check with your doctor or health care professional if you get an attack of severe diarrhea, nausea and vomiting, or if you sweat a lot. The loss of too much body fluid can make it dangerous for you to take this medicine.
You may get dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.
Common and Rare Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
black, tarry stools
bloating or swelling of the face, arms, hands, lower legs, or feet
blood in the urine or stools
burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
decreased awareness or responsiveness
decreased urine output
difficult or labored breathing
difficulty with moving
fast, slow, or irregular heartbeat
loss of consciousness
lower back or side pain
muscle spasms (tetany) or twitching
numbness or tingling in the hands, feet, or lips
painful or difficult urination
pinpoint red spots on the skin
pounding in the ears
rapid weight gain
tightness in the chest
tingling of the hands or feet
troubled breathing with exertion
ulcers, sores, or white spots in the mouth
unsteadiness or awkwardness
unusual bleeding or bruising
unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
unusual tiredness or weakness
unusual weight gain or loss
muscle pain or cramps
painful blisters on the trunk of the body
weakness in the arms, hands, legs, or feet
general feeling of discomfort or illness
general feeling of tiredness or weakness
stomach pain, continuing
thickening of bronchial secretions
yellow eyes or skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
body aches or pain
flushed, dry skin
fruit-like breath odor
loss of appetite
loss of voice
pain in the arms or legs
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.