Availability: Generic ergotamine/caffeine has been discontinued. Cafergot is the only ergotamine/caffeine tablet currently available. Learn More
What should I watch for?
Check with your doctor or health care professional if you do not get relief from your headaches after using this medicine. You may need to be changed to a different kind of medicine to treat your migraines.
This medicine decreases the circulation of blood to your skin, fingers, and toes. You may get more sensitive to the cold. Elderly patients are more likely to feel this effect. Dress warmly and avoid long exposure to the cold.
This medicine contains caffeine. Limit your intake of caffeinated beverages on the days that you use this medicine.
If you take migraine medicines for 10 or more days a month, your migraines may get worse. Keep a diary of headache days and medicine use. Contact your healthcare professional if your migraine attacks occur more frequently.
Common and Rare Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if the following side effects occur, because they may mean that you are developing a problem with blood circulation:
Less common or rare
Anxiety or confusion (severe)
change in vision
increase in blood pressure
red or violet-colored blisters on the skin of the hands or feet
Get emergency help immediately if any of the following symptoms of overdose occur:
Less common or rare
dizziness, drowsiness, or weakness (severe), occurring together with other signs of overdose or of problems with blood circulation
fast or slow heartbeat
headaches, more often and/or more severe than before
problems with moving bowels, occurring together with pain or discomfort in the rectum (with rectal suppositories only)
shortness of breath
The following side effects may go away after a little while. Do not take any more medicine while they are present. If any of them occur together with other signs of problems with blood circulation, check with your doctor right away. Even if any of the following side effects occur without other signs of problems with blood circulation, check with your doctor if any of them continue for more than one hour:
Coldness, numbness, or tingling in fingers, toes, or face
itching of skin
weakness in legs
Check with your doctor as soon as possible if any of the following side effects occur:
Swelling of face, fingers, feet, or lower legs
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
nervousness or restlessness
difficulty in moving bowels
irregular bowel movements
After you stop taking this medicine, your body may need time to adjust. The length of time this takes depends on the amount of medicine you were taking and how long you took it. During this time check with your doctor if your headaches begin again or worsen.
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.