Buprenex Side Effects
What should I watch for?
Tell your doctor or health care professional if your pain does not go away, if it gets worse, or if you have new or a different type of pain. You may develop tolerance to the medicine. Tolerance means that you will need a higher dose of the medicine for pain relief. Tolerance is normal and is expected if you take this medicine for a long time.
Do not suddenly stop taking your medicine because you may develop a severe reaction. Your body becomes used to the medicine. This does NOT mean you are addicted. Addiction is a behavior related to getting and using a drug for a non-medical reason. If you have pain, you have a medical reason to take pain medicine. Your doctor will tell you how much medicine to take. If your doctor wants you to stop the medicine, the dose will be slowly lowered over time to avoid any side effects.
If you are also taking a narcotic medicine for pain or cough or another medicine that also causes drowsiness, you may have more side effects. Give your health care provider a list of all medicines you use. Your doctor will tell you how much medicine to take. Do not take more medicine than directed. Call emergency for help if you have problems breathing or unusual sleepiness.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
This medicine will cause constipation. Try to have a bowel movement at least every 2 to 3 days. If you do not have a bowel movement for 3 days, call your doctor or health care professional.
Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.
Common and Rare Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
relaxed and calm feeling
Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
bluish color of the fingernails, lips, skin, palms, or nail beds
burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
chest pain or discomfort
difficult or labored breathing
feeling, seeing, or hearing things that are not there
feeling that others are watching you or controlling your behavior
feeling that others can hear your thoughts
severe mood or mental changes
tightness of the chest
Incidence not known
darkening of the skin
deep or fast breathing with dizziness
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
loss of appetite
loss of muscle coordination
talking or acting with excitement which you cannot control
unusual tiredness or weakness
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Constricted, pinpoint, or small pupils (black part of the eye)
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
extremely shallow or slow breathing
Burning, dry, or itching eyes
continuing ringing or buzzing or other unexplained noise in the ears
decrease in the frequency of urination
decrease in urine volume
difficulty in passing urine (dribbling)
discharge, excessive tearing
false or unusual sense of well-being
fast, pounding, or irregular heartbeat or pulse
feeling of warmth
itching of the skin
pounding in the ears
redness of the face, neck, arms, and occasionally, upper chest
redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid
Incidence not known
bluish lips or skin
change in vision
excess air or gas in the stomach or intestines
feeling of fullness
feeling of unreality
general feeling of discomfort or illness
hives or welts
paleness of the skin
redness of the skin
sense of detachment from self or body
stomach discomfort, upset, or pain
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.