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Bosentan
Specialty Drug

Tracleer

BOSENTAN is used to treat a serious heart and lung disorder called pulmonary hypertension. This medicine may help to increase your ability to exercise and improve your breathing. Compare endothelin antagonists.

Bosentan Side Effects

What should I watch for?

Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.

Do not become pregnant while taking this medicine. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information.

This medicine has caused reduced sperm counts in some men. This may interfere with the ability to father a child. You should talk to your doctor or health care professional if you are concerned about your fertility.

You may need blood work done while you are taking this medicine.

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Common and Rare Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Blurred vision

confusion

dizziness

dark urine

faintness or lightheadedness when getting up from a lying or sitting position

fever with or without chills

light-colored stools

loss of appetite

nausea

stomach pain

sudden sweating

unusual tiredness or weakness

vomiting

yellow eyes or skin

Less common

Swelling

Incidence not known

Black, tarry stools

bleeding gums

blood in the urine or stools

blue lips and fingernails

chest pain

chills

clay-colored stools

coughing that sometimes produces a pink frothy sputum

coughing up blood

dark urine

decrease in the amount of urine

difficult, fast, or noisy breathing

fainting

fast heartbeat

fatigue on exertion

fever

headache

hives, itching, skin rash

hoarseness

increased sweating

irritation

joint pain, stiffness, or swelling

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

noisy, rattling breathing

pale skin

pinpoint red spots on the skin

redness of the skin

shortness of breath

swelling of the eyelids, face, lips, hands, fingers, legs, ankles, or feet

tightness in the chest

troubled breathing at rest or exertion

troubled breathing or swallowing

unpleasant breath odor

unusual bleeding or bruising

vomiting of blood

weight gain

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Increased heart rate

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Fast, irregular, pounding, or racing heartbeat or pulse

feeling of warmth

muscle aches

redness of the face, neck, arms, and occasionally upper chest

sore throat

stuffy or runny nose

Less common

Belching

heartburn

indigestion

stomach discomfort, upset, or pain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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