The GoodRx Prescription Savings Blog

The latest updates on prescription drugs and ways to save from the GoodRx medical team

When Should I Stop Taking Aspirin Before My Surgery?

by Roni Shye on February 10, 2015 at 11:23 am

If you are taking daily aspirin and are about to have a non-cardiac surgery we now have a firm answer: 7 days.

Many of you scheduled to undergo surgery are taking aspirin for prevention of cardiovascular disease. The risk of aspirin prior to surgery was just confirmed in a large trial called the POISE-2 trial. There was no benefit to taking an aspirin up until surgery and there were, not surprisingly, risks. As expected, major bleeding was more common in the aspirin group (4.6 versus 3.8 percent). Patients with an indication for long-term aspirin usage who stop taking aspirin prior to surgery should have their aspirin re-started when the risk of major bleeding after surgery has passed.

Prior to POISE-2, the potential harm from taking aspirin up until your surgery was not well studied, and there was evidence from small studies both against and in favor of its use. Now we know. Stop your aspirin seven days before your surgery.

Dr O.

Copyright ©2015 GoodRx, Inc.

This information is for informational purposes only and is not meant to be a substitute for professional medical advice, diagnosis or treatment. GoodRx is not offering advice, recommending or endorsing any specific prescription drug, pharmacy or other information on the site. GoodRx provides no warranty for any of the pricing data or other information. Please seek medical advice before starting, changing or terminating any medical treatment. Third party logos, trademarks, brand names and images contained on are for demonstration purposes only and are owned by their respective rights holders, who are not affiliated with this Site.