The GoodRx Prescription Savings Blog

The latest updates on prescription drugs and ways to save from the GoodRx medical team

Nexium (Esomeprazole Magnesium) vs Esomeprazole Strontium: What’s the Difference?

by The GoodRx Pharmacist on July 24, 2014 at 9:51 am

With almost identical active ingredient names, these medications can be easy to confuse—but esomeprazole strontium is not a generic equivalent to Nexium. Although both treat GERD (heartburn), they are available in different strengths and have different advantages.

What is GERD?

GERD or gastroesophageal reflux disease is more commonly known as heartburn. Heartburn is a form of indigestion in which your stomach acid comes back up into the esophagus.

What are the dosage forms for these medications?
Nexium (esomeprazole magnesium) is available as a capsule and an oral suspension packet. Esomeprazole strontium is available as a capsule only.

What are the strengths for these medications?
Nexium (esomeprazole magnesium) is available in 20 mg and 40 mg strengths, which esomeprazole strontium is available in a 49.3 mg strength only.

What type of medication are esomeprazole magnesium and strontium?

Both Nexium (esomeprazole magnesium) and esomperazole strontium are considered PPI(s) or Pronton Pump Inhibitor(s).

PPIs work by shutting off the “pumps” in the body responsible for releasing acid in the stomach. They decrease the amount of acid in the stomach and help control the symptoms of acid reflux or GERD.

What are the advantages of using Nexium (esomeprazole magnesium)?

  • Nexium (esomeprazole magnesium) 20 mg capsules are now available over-the-counter and they do NOT require a prescription. Nexium 24HR can be found in your pharmacy or grocery store aisles in the stomach section. Check out our previous article for more information.
  • Nexium’s manufacturer, AztraZeneca, has a savings card program for the prescription version. For those who qualify, you may pay as little as $25 per month for your prescription.
  • Nexium may be going generic soon! The anticipated generic launch date was May 2014, so keep your eyes open for a potential generic product launch in the near future.

What are the advantages of using esomeprazole strontium?

  • Esomeprazole strontium is already available generically. Generic medications provide a potential cost savings to you through a lower cash price or insurance co-pay without needing to use a manufacturer discount.

Copyright ©2015 GoodRx, Inc.

This information is for informational purposes only and is not meant to be a substitute for professional medical advice, diagnosis or treatment. GoodRx is not offering advice, recommending or endorsing any specific prescription drug, pharmacy or other information on the site. GoodRx provides no warranty for any of the pricing data or other information. Please seek medical advice before starting, changing or terminating any medical treatment. Third party logos, trademarks, brand names and images contained on are for demonstration purposes only and are owned by their respective rights holders, who are not affiliated with this Site.